A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis
Sponsored by iCell Gene Therapeutics
About this study
This Phase IIa, open-label, single-arm study includes an initial Safety Run-In followed by dose expansion to evaluate the safety, tolerability, cellular kinetics, pharmacodynamics, and preliminary clinical activity of a single infusion of ICG318 in participants with refractory SLE, with or without LN. Participants will receive protocol-specified lymphodepletion followed by ICG318 at the recommended Phase 2 dose.
Enrolling at this location
NorthWell
New Hyde Park, New York
I'm interestedThis study also enrolls at 3 other locations. See all.
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Trial data sourced from ClinicalTrials.gov.