Back to Clinical Trials
Phase 3Recruiting

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

Sponsored by Eli Lilly and Company

About this study

The main purpose of this study is to determine if participants who previously took donanemab get clinical benefit when they receive annual doses. For each participant, the study will last up to 2.5 years and will include 6 visits.

Where this study is enrolling (48)

  • Banner Alzheimer's Institute

    Phoenix, Arizona

    Call 602-839-6900

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Healthy Brain Clinic

    Long Beach, California

    Call 562-606-5999

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Syrentis Clinical Research

    Santa Ana, California

    Call 714-542-3008

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Clinical Trials Research

    Sacramento, California

    Call 916-434-8230

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Artemis Institute for Clinical Research

    Riverside, California

    Call 951-374-1190

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

Show all 48 locations

  • Care Access - Huntington Beach

    Huntington Beach, California

    Call 714-378-2440

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Providence Medical Foundation

    Santa Rosa, California

    Call 707-521-3830

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Irvine Clinical Research

    Irvine, California

    Call 949-753-1663

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Artemis Institute for Clinical Research

    San Diego, California

    Call 858-278-3647

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Infectious Disease Doctors Medical Group, APC

    Walnut Creek, California

    Call 925-947-2334

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • VIN-Andrew Lerman

    Miami, Florida

    Call 786-655-8010

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Bradenton Research Center, Inc.

    Bradenton, Florida

    Call 941-708-0005

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Care Access - Tampa

    Tampa, Florida

    Call 877-791-0656

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Charter Research - Orlando

    Orlando, Florida

    Call 407-337-3000

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Charter Research - The Villages

    The Villages, Florida

    Call 352-441-2000

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Conquest Research

    Winter Park, Florida

    Call 407-916-0060

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Emerald Coast Neurology - Airport Boulevard

    Pensacola, Florida

    Call 850-438-1136

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Finlay Medical Research

    Greenacres City, Florida

    Call 561-766-2181

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Headlands Research Orlando

    Orlando, Florida

    Call 407-705-3471

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Indago Research & Health Center, Inc

    Miami Lakes, Florida

    Call 305-825-6588

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Jacksonville Center for Clinical Research

    Jacksonville, Florida

    Call 904-730-0101

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • K2 Medical Research ORLANDO

    Maitland, Florida

    Call 407-500-5252

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • K2 Medical Research - Tampa

    Tampa, Florida

    Call 813-800-5252

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Progressive Medical Research

    Port Orange, Florida

    Call 386-304-7070

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Suncoast Clinical Research, Inc.

    New Port Richey, Florida

    Call 727-849-4131

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • VIN - Aventura

    Aventura, Florida

    Call 305-933-5993

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Adult Medicine of Lake County, Inc.

    Mt. Dora, Florida

    Call 352-383-8222

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • North Georgia Clinical Research

    Woodstock, Georgia

    Call 678-494-5735

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Center for Advanced Research & Education

    Gainesville, Georgia

    Call 770-534-5154

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Northwest Clinical Trials

    Boise, Idaho

    Call 208-685-0600

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Great Lakes Clinical Trials - Andersonville

    Chicago, Illinois

    I'm interested

  • Josephson Wallack Munshower Neurology, PC

    Indianapolis, Indiana

    Call 317-537-6099

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Care Access - South Indianapolis

    Indianapolis, Indiana

    Call 877-791-0656

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Covenant Medical Center

    Waterloo, Iowa

    Call 319-272-2112

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Care Access - Lake Charles (Bayou Pines)

    Lake Charles, Louisiana

    Call 337-602-6642

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • MedVadis Research Corporation

    Waltham, Massachusetts

    Call 617-744-1310

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Boston Center for Memory

    Newton, Massachusetts

    Call 617-699-6927

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Revival Research Institute, LLC

    Southfield, Michigan

    Call 586-276-7453

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Citizens Memorial Hospital District

    Bolivar, Missouri

    Call 417-328-7781

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Vector Clinical Trials

    Las Vegas, Nevada

    Call 702-750-000

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Monroe Biomedical Research

    Monroe, North Carolina

    Call 704-283-7359

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Care Access - Lima

    Lima, Ohio

    Call 877-791-0656

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • NDx Clinical Research, Inc.

    Dayton, Ohio

    Call 937-224-8200

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Gadolin Research

    Beaumont, Texas

    Call 409-331-6040

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Consano Clinical Research, LLC

    Shavano Park, Texas

    Call 210-545-4900

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Senior Adults Specialty Research

    Austin, Texas

    Call 512-407-8628

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • The University of Texas Health Science Center at Houston

    Houston, Texas

    Call 713-486-0536

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Universal Research Group

    Tacoma, Washington

    Call 253-882-1070

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

Who can participate

Inclusion criteria

  • ✓Have completed study AACM Addendum 7.
  • ✓Have a reliable study partner and backup study partner familiar with overall function and behavior, such as day-to-day activities and cognitive abilities.
  • ✓Are individuals assigned female at birth who are not of childbearing potential, or are individuals assigned male at birth.
  • ✓Contraceptive use by participants should be consistent with local regulations regarding the methods of contraception for those participating in clinical studies.

Exclusion criteria

  • ✕Current serious or unstable illnesses that, in the investigator's opinion, could interfere with participation in this study.
  • ✕Have any contraindications for magnetic resonance imaging (MRI), including claustrophobia or the presence of contraindicated metal (ferromagnetic) implants/cardiac pacemaker.
  • ✕Have any intracranial abnormality or lesion, including but not limited to macrohemorrhage, inflammation, or structural findings that, in the opinion of the investigator, may pose an unacceptable safety risk to the participant. Screening MRI finding of amyloid-related imaging abnormalities with edema (ARIA-E) may be monitored for resolution.
  • ✕Contraindication to florbetapir F 18 PET.
  • ✕Have had history of amyloid-targeting therapy treatment outside donanemab trials.
  • ✕Have participated, within the last 30 days, in a clinical trial involving a study intervention judged not to be scientifically or medically compatible with this study.

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.