A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
Sponsored by Eli Lilly and Company
About this study
The purpose of this study is to evaluate how well LY4213663 is tolerated and what side effects may occur in healthy participants and participants with rheumatoid arthritis (RA). The study drug will be administered either subcutaneously (SC) (under the skin) or intravenously (IV) (into a vein in the arm). Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body. The study will last approximately 33 weeks excluding screening.
Where this study is enrolling (9)
- Call 256-236-0055, ext 101
Pinnacle Research Group, LLC
Anniston, Alabama
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Arizona Research Center
Phoenix, Arizona
- Call 727-466-0078
Clinical Research of West Florida, Inc. (Clearwater)
Clearwater, Florida
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- Call 305-220-2727, Ext 802
Advanced Pharma CR, LLC
Miami, Florida
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- Call 866-429-3700
Fortrea Clinical Research Unit
Daytona Beach, Florida
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Show all 9 locations
- Call 754-248-3589
GNP Research at Mark Jaffe, MD
Cooper City, Florida
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- Call 305-330-9977
Floridian Clinical Research
Miami Lakes, Florida
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- Call 704-526-6864
AGA Clinical Trials
Hialeah, Florida
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- Call 702-832-1369
Oasis Clinical Research
Las Vegas, Nevada
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Who can participate
Inclusion criteria
- ✓Have a body mass index (BMI) of 18.0 to 32.0 kilogram per square meter (kg/m²), inclusive
- ✓Part C and D Only:
- ✓Have a body weight at least 50 kilograms and BMI within the range 18.0 to 40.0 kg/m² (inclusive) at screening
- ✓Have a diagnosis of adult-onset RA for at least 3 months prior to screening
Exclusion criteria
- ✕Healthy Participants for SAD Part A and MAD Part B Only:
- ✕Have a history or presence of cardiovascular, respiratory, hepatic, ophthalmological, renal, gastrointestinal, endocrine, hematological, neurological, or psychiatric disorders capable of significantly altering the absorption, metabolism, or elimination of drugs
- ✕Participants with RA for Parts C and D Only:
- ✕Have Class 4 RA according to American College of Rheumatology (ACR) revised criteria
- ✕Have a 12-lead electrocardiogram (ECG) abnormality at screening
- ✕Have a current or recent acute active infection
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Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.