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A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

Sponsored by Eli Lilly and Company

About this study

This study looks at how well a medicine called orforglipron works compared to another medicine called dulaglutide in pediatric participants aged 10 to less than 18 years with type 2 diabetes. The study will also check how safe these medicines are and how the body processes them. Participation in the study will last about 61 weeks.

Where this study is enrolling (15)

  • Sutter Valley Medical Foundation (SVMF) Pediatric Endocrinology

    Sacramento, California

    Call 9164261902

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  • Rady Children's Hospital

    San Diego, California

    Call 8589668940

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  • CenExel iResearch, LLC

    Decatur, Georgia

    Call 4045371281

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  • Children's Healthcare of Atlanta - Center for Advanced Pediatrics (CAP)

    Atlanta, Georgia

    Call 404-256-2593

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  • Medical Research Partners

    Ammon, Idaho

    Call (208) 522-4600

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Show all 15 locations
  • Cotton O'Neil Diabetes & Endocrinology

    Topeka, Kansas

    Call 785-354-9591

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  • Advantage Clinical Trials

    The Bronx, New York

    Call 917-962-0234

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  • Central States Research

    Tulsa, Oklahoma

    Call 918-645-5400

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  • Frontier Clinical Research, LLC

    Smithfield, Pennsylvania

    Call 7245698036

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  • Vanderbilt Health One Hundred Oaks

    Nashville, Tennessee

    Call 2252265662

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  • Victoria Clinical Research Group

    Victoria, Texas

    Call 3612107869

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  • Consano Clinical Research, LLC

    Shavano Park, Texas

    Call 210-545-4900

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  • Driscoll Children's Hospital

    Corpus Christi, Texas

    Call 3617397250

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  • Gadolin Research

    Beaumont, Texas

    Call 409-331-6040

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  • Proactive Clinical Research LLC

    Edinburg, Texas

    Call 956-731-1260

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Who can participate

Inclusion criteria

  • ✓Have type 2 diabetes treated with diet and exercise and metformin and/or basal insulin
  • ✓Have HbA1c \> 6.5% to ≤ 11.0% at screening
  • ✓Have a body weight ≥50 kilograms (kg) (110 pounds) and a body mass index (BMI) of \>85th percentile

Exclusion criteria

  • ✕Have type 1 diabetes
  • ✕After the type 2 diabetes diagnosis, have a history of diabetic ketoacidosis or hyperosmolar syndrome
  • ✕Have had at least one episode of severe hypoglycemia and/or at least one episode of hypoglycemic unawareness within the last 6 months before screening
  • ✕Have a history of pancreatitis or gallbladder disease
  • ✕Have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)
  • ✕Have received treatment with any glucose-lowering agent(s) other than metformin, basal insulin, or (SGLT2) inhibitors within 90 days prior to screening
  • ✕Have been treated with prescription drugs or over-the-counter medications that promote weight loss within 90 days prior to screening

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.