A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Sponsored by Eli Lilly and Company
About this study
This study looks at how well a medicine called orforglipron works compared to another medicine called dulaglutide in pediatric participants aged 10 to less than 18 years with type 2 diabetes. The study will also check how safe these medicines are and how the body processes them. Participation in the study will last about 61 weeks.
Where this study is enrolling (15)
- Call 9164261902
Sutter Valley Medical Foundation (SVMF) Pediatric Endocrinology
Sacramento, California
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- Call 8589668940
Rady Children's Hospital
San Diego, California
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- Call 4045371281
CenExel iResearch, LLC
Decatur, Georgia
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- Call 404-256-2593
Children's Healthcare of Atlanta - Center for Advanced Pediatrics (CAP)
Atlanta, Georgia
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- Call (208) 522-4600
Medical Research Partners
Ammon, Idaho
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Show all 15 locations
- Call 785-354-9591
Cotton O'Neil Diabetes & Endocrinology
Topeka, Kansas
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- Call 917-962-0234
Advantage Clinical Trials
The Bronx, New York
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- Call 918-645-5400
Central States Research
Tulsa, Oklahoma
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- Call 7245698036
Frontier Clinical Research, LLC
Smithfield, Pennsylvania
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- Call 2252265662
Vanderbilt Health One Hundred Oaks
Nashville, Tennessee
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- Call 3612107869
Victoria Clinical Research Group
Victoria, Texas
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- Call 210-545-4900
Consano Clinical Research, LLC
Shavano Park, Texas
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- Call 3617397250
Driscoll Children's Hospital
Corpus Christi, Texas
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- Call 409-331-6040
Gadolin Research
Beaumont, Texas
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- Call 956-731-1260
Proactive Clinical Research LLC
Edinburg, Texas
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Who can participate
Inclusion criteria
- ✓Have type 2 diabetes treated with diet and exercise and metformin and/or basal insulin
- ✓Have HbA1c \> 6.5% to ≤ 11.0% at screening
- ✓Have a body weight ≥50 kilograms (kg) (110 pounds) and a body mass index (BMI) of \>85th percentile
Exclusion criteria
- ✕Have type 1 diabetes
- ✕After the type 2 diabetes diagnosis, have a history of diabetic ketoacidosis or hyperosmolar syndrome
- ✕Have had at least one episode of severe hypoglycemia and/or at least one episode of hypoglycemic unawareness within the last 6 months before screening
- ✕Have a history of pancreatitis or gallbladder disease
- ✕Have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)
- ✕Have received treatment with any glucose-lowering agent(s) other than metformin, basal insulin, or (SGLT2) inhibitors within 90 days prior to screening
- ✕Have been treated with prescription drugs or over-the-counter medications that promote weight loss within 90 days prior to screening
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.