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Phase 3Recruiting

A Study to Compare the Efficacy and Safety of BMS-986489 (Atigotatug+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS).

Sponsored by Bristol-Myers Squibb

About this study

The Purpose of the Study is to Compare the Efficacy and Safety of BMS-986489 (Anti-fucosyl-GM1+ Nivolumab Fixed Dose Combination) in Combination with Carboplatin plus Etoposide to that of Atezolizumab with Carboplatin plus Etoposide as First-Line Therapy in Participants with Extensive-Stage Small Cell Lung Cancer.

Where this study is enrolling (18)

  • Southern Cancer Center, PC

    Daphne, Alabama

    Call 111-111-1111

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  • Mid Florida Hematology and Oncology Center

    Orange City, Florida

    Call 407-353-1915

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  • Florida Cancer Specialists - North

    St. Petersburg, Florida

    Call 727-216-1143

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  • Florida Cancer Specialists - South

    Fort Myers, Florida

    Call 239-274-9930

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  • Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital

    Marietta, Georgia

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  • Illinois Cancer Care

    Peoria, Illinois

    Call 309-243-3000

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  • University of New Mexico Comprehensive Cancer Center

    Albuquerque, New Mexico

    Call 505-570-5835

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  • Duke Cancer Institute

    Durham, North Carolina

    Call 919-684-8239

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  • Sanford Fargo Medical Center

    Fargo, North Dakota

    Call 000-000-0000

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  • Sanford Medical Center

    Bismarck, North Dakota

    Call 701-323-5741

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  • Oncology Hematology Care

    Cincinnati, Ohio

    Call 513-751-2273

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  • Sanford Cancer Center

    Sioux Falls, South Dakota

    Call 605-209-4092

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  • SCRI Oncology Partners

    Nashville, Tennessee

    Call 615-329-7274

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  • Texas Oncology - Central/South Texas

    Austin, Texas

    Call 512-427-9400

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  • Texas Oncology - Northeast Texas

    Tyler, Texas

    Call 903-579-9800

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  • Oncology & Hematology Associates of Southwest Virginia, Inc.

    Roanoke, Virginia

    Call 540-381-5291

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  • Swedish Medical Center

    Seattle, Washington

    Call 206-386-2457

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  • Swedish Cancer Institute - Edmonds

    Edmonds, Washington

    Call 206-386-2457

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Who can participate

Inclusion criteria

  • ✓Participants must have diagnosis of Extensive-Stage Small Cell Lung Cancer (ES-SCLC).
  • ✓Participants must be Healthy enough to do their normal activities with little or no help based on the ECOG performance scale.
  • ✓Participants must have at least one tumor that can be measured using special imaging techniques like a CT scan or MRI at a site other than the brain and nervous system

Exclusion criteria

  • ✕Participants have already received certain types of treatment for extensive stage small cell lung cancer
  • ✕Participants have certain health conditions, like spread of small cell lung cancer to the brain that are causing symptoms, certain lung diseases, heart diseases, infections, autoimmune diseases, other cancers, or a type of nerve damage called peripheral sensory neuropathy
  • ✕Other protocol-defined Inclusion/Exclusion criteria apply.

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.