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Phase 3Recruiting

A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)

Sponsored by Bristol-Myers Squibb

About this study

A study to evaluate Pumitamig versus Durvalumab following concurrent chemoradiation therapy in participants with unresectable stage III Non-small Cell Lung Cancer (NSCLC)

Where this study is enrolling (25)

  • Southern Cancer Center Pc

    Daphne, Alabama

    Call 111-111-1111

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  • Intermountain Health Cancer Center Lutheran Hospital

    Golden, Colorado

    Call 303-403-7333

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  • Medical Oncology Hematology Consultants, PA

    Newark, Delaware

    Call 302-366-1200

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  • Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital

    Marietta, Georgia

    I'm interested
  • University of Chicago Medical Center

    Chicago, Illinois

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Show all 25 locations
  • Illinois Cancer Care

    Peoria, Illinois

    Call 309-243-3000

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  • Fort Wayne Medical Oncology and Hematology

    Fort Wayne, Indiana

    Call 260-436-0800

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  • University of Kentucky Chandler Medical Center

    Lexington, Kentucky

    Call 859-218-6704

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  • Optum Medical Care, PC

    Westbury, New York

    Call 914-242-2991

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  • Cleveland Clinic

    Cleveland, Ohio

    Call 216-636-6888

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  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio

    Call 301-980-8969

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  • Cleveland Clinic - Hillcrest Hospital

    Mayfield Heights, Ohio

    Call 216-636-6888

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  • The Christ Hospital

    Cincinnati, Ohio

    Call 513-321-4333

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  • Oncology Associates Of Oregon, Pc

    Eugene, Oregon

    Call 541-683-5001

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  • Northwest Cancer Specialists, P.C.

    Happy Valley, Oregon

    Call 503-885-5411

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  • Tennessee Oncology

    Nashville, Tennessee

    Call 615-322-4967

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  • SCRI Oncology Partners

    Nashville, Tennessee

    Call 615-329-7274

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  • The Center For Cancer And Blood Disorders

    Fort Worth, Texas

    Call 817-759-7000

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  • The University of Texas-MD Anderson Cancer Center

    Houston, Texas

    Call 877-632-6789

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  • Texas Oncology

    Denton, Texas

    Call 214-370-1000

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  • Texas Oncology - Amarillo Cancer Center

    Amarillo, Texas

    Call 000-000-0000

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  • Texas Oncology - Northeast Texas

    Tyler, Texas

    Call 903-579-9800

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  • Texas Oncology - San Antonio Medical Center

    San Antonio, Texas

    Call 210-656-7177

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  • Texas Oncology-Austin Central

    Austin, Texas

    Call 512-427-9400

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  • Blue Ridge Cancer Care

    Christiansburg, Virginia

    Call 540-381-5291

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Who can participate

Inclusion criteria

  • ✓Participants must have a histologically- or cytologically-confirmed diagnoses of non-small cell lung cancer (NSCLC) with unresectable Stage III disease.
  • ✓Participants must have received at least 2 cycles of platinum-based concurrent chemoradiotherapy (a total dose of radiation of at least 54 Gy).
  • ✓Participants must have no progressive disease (PD) following treatment with concurrent chemoradiotherapy (CCRT).
  • ✓Participants must have an Eastern Cooperative Oncology Group (ECOG) performance status (PS) score of 0 or 1.

Exclusion criteria

  • ✕Participants with non-squamous histology must not have documented Epidermal Growth Factor Receptor (EGFR) and anaplastic lymphoma kinase (ALK) rearrangements.
  • ✕Participants must not have an active autoimmune disease.
  • ✕Participants must not have significant cardiovascular impairment such as uncontrolled hypertension (despite optimal medical treatment), congestive heart failure, active coronary disease (within 6 months prior to randomization), ventricular arrhythmias, major thrombotic or embolic events or major hemorrhagic events within 6 months prior to randomization, or significant risk of pulmonary hemorrhage.
  • ✕Participants must not have advanced/clinically significant lung disease (within 6 months prior to randomization) or history of interstitial lung disease (ILD) or pneumonitis requiring treatment with systemic steroids (≥ Grade 2), or current or suspected ILD or pneumonitis.
  • ✕Participants must not have any prior anticancer therapy (outside of CCRT) for locally advanced Stage III disease.
  • ✕Other protocol-defined Inclusion/Exclusion criteria apply.

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.