A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.
Sponsored by Bristol-Myers Squibb
About this study
The purpose of this study is to evaluate the safety, tolerability, and efficacy of escalating doses of BMS-986463 in participants with select advanced malignant tumors.
Where this study is enrolling (3)
- Call 310-226-2905
USC/Norris Comprehensive Cancer Center
Los Angeles, California
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- Call 424-535-1874
Valkyrie Clinical Trials
Los Angeles, California
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- Call 551-996-5863
John Theurer Cancer Center at Hackensack University Medical Center
Hackensack, New Jersey
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Who can participate
Inclusion criteria
- ✓Participants must have an Eastern Cooperative Oncology Group Performance Status of 0 or 1.
- ✓Participants must have at least 1 lesion accessible for biopsy in addition to the target lesion, from which a fresh pre treatment biopsy must be obtained.
- ✓Participants must have an unresectable/metastatic carcinoma.
Exclusion criteria
- ✕Participants must not have Leptomeningeal metastases.
- ✕Participants must not have concurrent malignancy (present during screening) requiring treatment or history of prior malignancy active within 2 years prior to treatment.
- ✕Participants must not have had any prior radiation therapy within 2 weeks prior to start of study treatment.
- ✕Other protocol-defined Inclusion/Exclusion criteria apply.
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Trial data sourced from ClinicalTrials.gov.