American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
Sponsored by University of New Mexico
About this study
Despite many advances in our understanding of the natural history and progression of chronic kidney disease (CKD) and cardio vascular disease (CVD) in the parent CRIC study over the past 15 years, important questions about key risk factors for these diseases remain unanswered in the AI population. To address this burden of CKD in AI communities Investigators formed a consortium of investigators with extensive experience in conducting research of chronic diseases including diabetes, cardiovascular and kidney disease in AIs of Southwestern US. The proposed CRIC ancillary cohort study of 500 AIs (AI-CRIC) will rapidly improve our understanding of both potential risk factors for CKD progression, as well as the scope of this disease among AIs. This study leverages the current CRIC study and incorporates the planned activities of the next phase of the study - "CRIC 2018" - by implementing contemporary CRIC protocols for kidney and cardiovascular measurement and outcomes.
Investigators will conduct a longitudinal study of a CKD cohort of Southwest AIs to identify unique risk factors for CKD and CVD progression and compare CKD and CVD event rates and risk factors between AI and the populations represented in CRIC. Investigators will establish a specimen bank to support future ancillary studies designed to identify and examine biomarkers associated with the progression of CKD in AIs. At the Clinic Visit the following will occur: * weight is measured * blood pressure and heart rate are recorded * information about medical history and medication used recently * blood draw (about ½ cup) for the following tests: CBC (Complete Blood Count), tests of metabolism, and several other heart and kidney tests * blood pressure in the leg and arm calculated as the Ankle B…
Where this study is enrolling
- I'm interested
NIDDK-Phoenix Epidemiology and Clinical Research
Phoenix, Arizona
Who can participate
Inclusion criteria
- ✓Glomerular Filtration Rate (GFR): eGFR of =\>61\<80 and microalbuminuria \> 30 or eGRF of =\<60 (no microalbuminuria required).
Exclusion criteria
- ✕1. Unable or unwilling to provide informed consent
- ✕2. life expectancy \<3 years;
- ✕3. institutionalized subjects;
- ✕4. End stage renal disease or renal transplant;
- ✕5. renal cancer;
- ✕6. myeloma;
- ✕7. immunosuppression;
- ✕8. Polycystic kidney disease;
- ✕9. participation in any clinical trial,
- ✕10. current pregnancy
- ✕11. current incarceration.
- ✕12. Appears unlikely or unable to participate in the required study procedures as assessed by the investigator, study coordinator or designee.
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.