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Phase 3Recruiting

APPLE: Aspirin to Prevent Pregnancy Loss and Preeclampsia

Sponsored by University of Pennsylvania

About this study

The goal of this clinical trial is to investigate the effects of early initiation of double low-dose aspirin in pregnant women. The main questions it aims to answer are: Does this dose and timing of aspirin reduce the risk of pre-eclampsia compared to standard recommendations? Does this dose and timing of aspirin reduce the risk of pregnancy loss compared to standard recommendations? Participants will begin taking at no later than 6 weeks 6 days gestational age, either 162mg of aspirin through delivery or placebo until 12 weeks and then 81mg of aspirin through delivery.

Enrolling at this location

University of Pennsylvania

Philadelphia, Pennsylvania

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Trial data sourced from ClinicalTrials.gov.