De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
Sponsored by NRG Oncology
About this study
This Phase III Trial evaluates whether breast conservation surgery and endocrine therapy results in a non-inferior rate of invasive or non-invasive ipsilateral breast tumor recurrence (IBTR) compared to breast conservation with breast radiation and endocrine therapy.
Breast conservation therapy for early stage breast cancer has been an important achievement of oncology practice in the last half century and breast radiotherapy (RT) has been essential in its development. Several seminal randomized clinical trials conducted in the 1980's era demonstrated that breast radiotherapy following lumpectomy yielded overall survival outcomes equivalent to mastectomy for treatment of early stage invasive breast cancer leading to the National Institute of Health (NIH) Consensus Conference statement in 1991 supporting breast conservation treatment.This established lumpectomy with RT as an alternative to mastectomy and subsequently the rate of breast conservation for eligible breast cancer patients rose steadily. Shortly thereafter, investigators recognized that the t…
Where this study is enrolling (707)
- I'm interested
University of South Alabama Mitchell Cancer Institute
Mobile, Alabama
- I'm interested
Kingman Regional Medical Center
Kingman, Arizona
- I'm interested
Cancer Center at Saint Joseph's
Phoenix, Arizona
- Call 501-686-8274
University of Arkansas for Medical Sciences
Little Rock, Arkansas
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Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California
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- I'm interested
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California
- I'm interested
The Permanente Medical Group-Roseville Radiation Oncology
Roseville, California
- Call 831-462-7770
Dominican Santa Cruz Hospital
Santa Cruz, California
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Kaiser Permanente-Fresno
Fresno, California
- Call 916-734-3089
University of California Davis Comprehensive Cancer Center
Sacramento, California
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Kaiser Permanente-Fremont
Fremont, California
- I'm interested
Kaiser Permanente-Deer Valley Medical Center
Antioch, California
- I'm interested
Kaiser Permanente-Bellflower
Bellflower, California
- I'm interested
Sutter Pacific Medical Foundation
Santa Rosa, California
- I'm interested
Sutter Auburn Faith Hospital
Auburn, California
- I'm interested
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California
- I'm interested
Sutter Medical Center Sacramento
Sacramento, California
- I'm interested
Kaiser Permanente-Anaheim
Anaheim, California
- I'm interested
Kaiser Permanente San Leandro
San Leandro, California
- I'm interested
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California
- I'm interested
Kaiser Permanente Oakland-Broadway
Oakland, California
- Call 714-734-6220
Saint Joseph Hospital - Orange
Orange, California
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- Call 877-642-4691
Kaiser Permanente- Modesto MOB II
Modesto, California
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Kaiser Permanente Medical Center-Vacaville
Vacaville, California
- I'm interested
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California
- Call 877-642-4691
Kaiser Permanente- Marshall Medical Offices
Redwood City, California
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Fresno Cancer Center
Fresno, California
- I'm interested
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California
- I'm interested
California Pacific Medical Center-Pacific Campus
San Francisco, California
- Call 833-574-2273
Kaiser Permanente Fresno Orchard Plaza
Fresno, California
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- Call 877-642-4691
Kaiser Permanente Dublin
Dublin, California
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Kaiser Permanente Downtown Commons
Sacramento, California
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Kaiser Permanente Cancer Treatment Center
South San Francisco, California
- I'm interested
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, California
- I'm interested
PCR Oncology
Arroyo Grande, California
- I'm interested
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California
- I'm interested
Palo Alto Medical Foundation-Fremont
Fremont, California
- I'm interested
Rohnert Park Cancer Center
Rohnert Park, California
- Call 310-423-8965
Cedars Sinai Medical Center
Los Angeles, California
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- Call 818-981-3818
Cedars-Sinai Cancer - Tarzana
Tarzana, California
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Palo Alto Medical Foundation-Camino Division
Mountain View, California
- I'm interested
Palo Alto Medical Foundation Health Care
Palo Alto, California
- I'm interested
Ridley-Tree Cancer Center
Santa Barbara, California
- I'm interested
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California
- I'm interested
Mercy Cancer Center - Sacramento
Sacramento, California
- I'm interested
Mercy Cancer Center - Rocklin
Rocklin, California
- I'm interested
Mercy Cancer Center - Elk Grove
Elk Grove, California
- I'm interested
Mercy Cancer Center - Carmichael
Carmichael, California
- I'm interested
Memorial Medical Center
Modesto, California
- I'm interested
Woodland Memorial Hospital
Woodland, California
- I'm interested
Torrance Memorial Physician Network - Cancer Care
Torrance, California
- I'm interested
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California
- I'm interested
Sutter Solano Medical Center/Cancer Center
Vallejo, California
- I'm interested
South Sacramento Cancer Center
Sacramento, California
- Call 530-582-6450
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California
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- I'm interested
Stanford Cancer Center South Bay
San Jose, California
- I'm interested
Stanford Cancer Institute Palo Alto
Palo Alto, California
- I'm interested
Los Angeles General Medical Center
Los Angeles, California
- Call 707-967-3698
Saint Helena Hospital
St. Helena, California
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Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California
- I'm interested
Kaiser San Rafael-Gallinas
San Rafael, California
- I'm interested
Kaiser Permanente-Walnut Creek
Walnut Creek, California
- I'm interested
Kaiser Permanente-Vallejo
Vallejo, California
- I'm interested
Mercy San Juan Medical Center
Carmichael, California
- Call 510-745-6433
Washington Hospital
Fremont, California
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Kaiser Permanente-Stockton
Stockton, California
- Call 661-839-1810
USC Norris Santa Clarita Oncology
Santa Clarita, California
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- Call 323-865-0451
USC / Norris Comprehensive Cancer Center
Los Angeles, California
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Kaiser Permanente-South San Francisco
South San Francisco, California
- I'm interested
Kaiser Permanente-South Sacramento
Sacramento, California
- I'm interested
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California
- I'm interested
Sutter Roseville Medical Center
Roseville, California
- I'm interested
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California
- I'm interested
Kaiser Permanente-Santa Rosa
Santa Rosa, California
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Kaiser Permanente-San Francisco
San Francisco, California
- I'm interested
Kaiser Permanente-Roseville
Roseville, California
- I'm interested
Kaiser Permanente-Riverside
Riverside, California
- I'm interested
Kaiser Permanente-Richmond
Richmond, California
- I'm interested
Kaiser Permanente-Rancho Cordova Cancer Center
Rancho Cordova, California
- I'm interested
Kaiser Permanente-Ontario
Ontario, California
- I'm interested
Kaiser Permanente-Oakland
Oakland, California
- I'm interested
Kaiser Permanente-Modesto
Modesto, California
- I'm interested
Saint Francis Cancer Center
Colorado Springs, Colorado
- I'm interested
Longmont United Hospital
Longmont, Colorado
- Call 970-470-7170
Dillon Health Center/Shaw Cancer Center
Dillon, Colorado
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Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado
- Call 970-203-7083
Medical Center of the Rockies
Loveland, Colorado
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Lutheran Hospital - Cancer Centers of Colorado
Golden, Colorado
- I'm interested
Saint Anthony North Hospital
Westminster, Colorado
- I'm interested
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado
- Call 719-365-2406
UCHealth Memorial Hospital Central
Colorado Springs, Colorado
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- Call 720-848-0650
UCHealth University of Colorado Hospital
Aurora, Colorado
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- Call 970-569-7429
Shaw Cancer Center
Edwards, Colorado
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Rose Medical Center
Denver, Colorado
- Call 720-848-0650
UCHealth Highlands Ranch Hospital
Highlands Ranch, Colorado
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UCHealth Lone Tree Health Center
Lone Tree, Colorado
- I'm interested
UCHealth Greeley Hospital
Greeley, Colorado
- I'm interested
UCHealth - Cherry Creek
Denver, Colorado
- Call 970-297-6150
Poudre Valley Hospital
Fort Collins, Colorado
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Yale University
New Haven, Connecticut
- I'm interested
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut
- I'm interested
Smilow Cancer Hospital-Hamden Care Center
Hamden, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center-Fairfield
Fairfield, Connecticut
- I'm interested
Smilow Cancer Hospital-Orange Care Center
Orange, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut
- I'm interested
Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center at Long Ridge
Stamford, Connecticut
- I'm interested
Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut
- I'm interested
Yale-New Haven Hospital Saint Raphael Campus
New Haven, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut
- I'm interested
Smilow Cancer Hospital Care Center at Glastonbury
Glastonbury, Connecticut
- I'm interested
Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut
- Call 202-877-8839
MedStar Washington Hospital Center
Washington D.C., District of Columbia
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- Call 202-444-2223
MedStar Georgetown University Hospital
Washington D.C., District of Columbia
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- Call 202-741-2210
George Washington University Medical Center
Washington D.C., District of Columbia
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- I'm interested
Florida Cancer Specialists - Sarasota
Sarasota, Florida
- I'm interested
Florida Cancer Specialists - Venice Pinebrook
Venice, Florida
- I'm interested
Mount Sinai Comprehensive Cancer Center at Aventura
Aventura, Florida
- I'm interested
Winter Haven Hospital
Winter Haven, Florida
- Call 305-243-2647
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida
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- Call 305-243-2647
UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida
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UM Sylvester Comprehensive Cancer Center at Doral
Doral, Florida
- Call 305-243-2647
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida
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- Call 305-243-2647
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida
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Mount Sinai Medical Center
Miami Beach, Florida
- I'm interested
Saint Joseph's Hospital/Children's Hospital-Tampa
Tampa, Florida
- Call 941-200-1125
Intercoastal Medical Group - Cattleridge II
Sarasota, Florida
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- I'm interested
UF Health Cancer Institute - Gainesville
Gainesville, Florida
- Call 941-917-6519
Sarasota Memorial Health Care Center at University Parkway
Sarasota, Florida
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- Call 941-261-9000
Sarasota Memorial Hospital-Venice
N. Venice, Florida
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- Call 941-917-2225
Sarasota Memorial Hospital
Sarasota, Florida
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- I'm interested
Cleveland Clinic-Weston
Weston, Florida
- I'm interested
Health Central
Ocoee, Florida
- I'm interested
Orlando Health Cancer Institute
Orlando, Florida
- Call 863-680-7780
The Watson Clinic
Lakeland, Florida
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Regional Cancer Center-Lee Memorial Health System
Fort Myers, Florida
- Call 407-303-2200
AdventHealth Altamonte
Altamonte Springs, Florida
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AdventHealth Orlando
Orlando, Florida
- I'm interested
First Physicians Group - Silverstein Institute at Floyd Street
Sarasota, Florida
- Call 941-917-5400
First Physicians Group - Urology Robotic and Minimally Invasive Surgery
Sarasota, Florida
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- Call 941-917-8383
First Physicians Group-Sarasota
Sarasota, Florida
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Florida Cancer Specialists - Bradenton Cancer Center
Bradenton, Florida
- Call 941-957-1000
Florida Cancer Specialists - Sarasota Downtown
Sarasota, Florida
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Florida Cancer Specialists - Venice Island
Venice, Florida
- I'm interested
Northside Hospital-Alpharetta
Alpharetta, Georgia
- I'm interested
Piedmont Newnan Hospital
Newnan, Georgia
- I'm interested
Piedmont Hospital
Atlanta, Georgia
- Call 404-425-1800
Piedmont Henry Hospital
Stockbridge, Georgia
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Piedmont Fayette Hospital
Fayetteville, Georgia
- I'm interested
Northside Hospital-Cherokee
Canton, Georgia
- I'm interested
Emory Decatur Hospital
Decatur, Georgia
- I'm interested
Emory Johns Creek Hospital
Johns Creek, Georgia
- I'm interested
Emory Saint Joseph's Hospital
Atlanta, Georgia
- I'm interested
Emory University Hospital Midtown
Atlanta, Georgia
- I'm interested
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia
- I'm interested
Grady Health System
Atlanta, Georgia
- I'm interested
Northside Hospital-Forsyth
Cumming, Georgia
- I'm interested
Northside Hospital
Atlanta, Georgia
- I'm interested
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia
- I'm interested
Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii
- Call 808-522-4333
Straub Clinic and Hospital
Honolulu, Hawaii
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- Call 808-532-0315
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii
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- I'm interested
The Queen's Medical Center - West Oahu
‘Ewa Beach, Hawaii
- Call 808-547-6881
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii
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- Call 808-983-6090
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii
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- Call 808-487-7447
Queen's Cancer Center - Pearlridge
‘Aiea, Hawaii
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- Call 808-586-2979
University of Hawaii Cancer Center
Honolulu, Hawaii
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- Call 808-545-8548
Queen's Medical Center
Honolulu, Hawaii
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- Call 808-486-6000
Pali Momi Medical Center
‘Aiea, Hawaii
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- Call 808-531-8521
Queen's Cancer Center - Kuakini
Honolulu, Hawaii
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Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii
- Call 808-547-9816
Kuakini Medical Center
Honolulu, Hawaii
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Hawaii Cancer Care - Westridge
‘Aiea, Hawaii
- Call 808-535-7960
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii
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- Call 808-678-9000
The Cancer Center of Hawaii-Pali Momi
‘Aiea, Hawaii
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Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho
- I'm interested
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho
- I'm interested
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho
- I'm interested
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho
- I'm interested
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois
- I'm interested
Carle Physician Group-Effingham
Effingham, Illinois
- I'm interested
Carle Cancer Institute Normal
Normal, Illinois
- I'm interested
Carle Cancer Center
Urbana, Illinois
- I'm interested
Advocate Good Samaritan Hospital
Downers Grove, Illinois
- I'm interested
Carle BroMenn Medical Center
Normal, Illinois
- I'm interested
HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois
- I'm interested
Carle at The Riverfront
Danville, Illinois
- Call 800-323-8622
Advocate Christ Medical Center
Oak Lawn, Illinois
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Illinois CancerCare - Washington
Washington, Illinois
- I'm interested
Illinois CancerCare-Bloomington
Bloomington, Illinois
- I'm interested
Illinois CancerCare-Canton
Canton, Illinois
- I'm interested
Illinois CancerCare-Carthage
Carthage, Illinois
- I'm interested
Illinois CancerCare-Eureka
Eureka, Illinois
- I'm interested
Illinois CancerCare-Galesburg
Galesburg, Illinois
- I'm interested
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois
- I'm interested
Illinois CancerCare-Macomb
Macomb, Illinois
- I'm interested
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois
- I'm interested
Illinois CancerCare-Pekin
Pekin, Illinois
- I'm interested
Illinois CancerCare-Peoria
Peoria, Illinois
- I'm interested
Illinois CancerCare-Peru
Peru, Illinois
- I'm interested
Illinois CancerCare-Princeton
Princeton, Illinois
- I'm interested
Elmhurst Memorial Hospital
Elmhurst, Illinois
- Call (847) 425-3900
Edward Hospital/Cancer Center
Naperville, Illinois
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Edward Hospital/Cancer Center?Plainfield
Plainfield, Illinois
- I'm interested
The Carle Foundation Hospital
Urbana, Illinois
- I'm interested
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois
- I'm interested
Decatur Memorial Hospital
Decatur, Illinois
- I'm interested
Crossroads Cancer Center
Effingham, Illinois
- I'm interested
OSF Saint Francis Medical Center
Peoria, Illinois
- Call 708-226-4357
Loyola University Medical Center
Maywood, Illinois
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Memorial Hospital of Carbondale
Carbondale, Illinois
- I'm interested
Condell Memorial Hospital
Libertyville, Illinois
- I'm interested
Northwestern University
Chicago, Illinois
- I'm interested
Northwestern Medicine Orland Park
Orland Park, Illinois
- I'm interested
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois
- I'm interested
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois
- I'm interested
OSF Saint Joseph Medical Center
Bloomington, Illinois
- I'm interested
Centralia Oncology Clinic
Centralia, Illinois
- Call 312-695-1102
Northwestern Medicine Grayslake Outpatient Center
Grayslake, Illinois
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- Call 847-842-4847
Advocate Good Shepherd Hospital
Barrington, Illinois
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- Call 312-695-1102
Northwestern Medicine Glenview Outpatient Center
Glenview, Illinois
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SIH Cancer Institute
Carterville, Illinois
- I'm interested
Ingalls Memorial Hospital
Harvey, Illinois
- Call (312) 864-0200
John H Stroger Jr Hospital of Cook County
Chicago, Illinois
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- I'm interested
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois
- I'm interested
Cancer Care Center of O'Fallon
O'Fallon, Illinois
- I'm interested
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois
- I'm interested
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois
- I'm interested
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois
- I'm interested
Advocate Outpatient Center - Aurora
Aurora, Illinois
- Call 847-384-3621
Advocate Lutheran General Hospital
Park Ridge, Illinois
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Advocate Illinois Masonic Medical Center
Chicago, Illinois
- I'm interested
University of Chicago Comprehensive Cancer Center
Chicago, Illinois
- I'm interested
University of Chicago Medicine-Orland Park
Orland Park, Illinois
- Call 844-793-0745
Midwestern Regional Medical Center
Zion, Illinois
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- I'm interested
Advocate High Tech Medical Park
Palos Heights, Illinois
- I'm interested
UW Health Carbone Cancer Center Rockford
Rockford, Illinois
- I'm interested
Methodist Medical Center of Illinois
Peoria, Illinois
- I'm interested
AMG Libertyville - Oncology
Libertyville, Illinois
- I'm interested
AMG Crystal Lake - Oncology
Crystal Lake, Illinois
- I'm interested
Rush MD Anderson Cancer Center
Chicago, Illinois
- Call 708-799-9995
Advocate South Suburban Hospital
Hazel Crest, Illinois
This research site can be reached directly by phone. Call to ask about this study.
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- Call 847-429-2907
Advocate Sherman Hospital
Elgin, Illinois
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- I'm interested
Saint Mary Medical Center
Hobart, Indiana
- Call 219-836-3349
The Community Hospital
Munster, Indiana
This research site can be reached directly by phone. Call to ask about this study.
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- Call 219-924-8178
Northwest Oncology LLC
Dyer, Indiana
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Northwest Cancer Center - Valparaiso
Valparaiso, Indiana
- Call 219-310-2550
Northwest Cancer Center - Main Campus
Crown Point, Indiana
This research site can be reached directly by phone. Call to ask about this study.
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- Call 317-834-3603
Franciscan Health Mooresville
Mooresville, Indiana
This research site can be reached directly by phone. Call to ask about this study.
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- Call 317-528-7060
Franciscan Health Indianapolis
Indianapolis, Indiana
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Reid Health
Richmond, Indiana
- Call 219-947-1795
Northwest Cancer Center - Hobart
Hobart, Indiana
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- I'm interested
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana
- I'm interested
Women's Diagnostic Center - Munster
Munster, Indiana
- I'm interested
UChicago Medicine Northwest Indiana
Crown Point, Indiana
- I'm interested
Saint Luke's Hospital
Cedar Rapids, Iowa
- Call 515-241-3305
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-6727
Iowa Methodist Medical Center
Des Moines, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
Greater Regional Medical Center
Creston, Iowa
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- I'm interested
McFarland Clinic - Ames
Ames, Iowa
- Call 515-241-3305
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-282-2200
Broadlawns Medical Center
Des Moines, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
Mercy Medical Center - Des Moines
Des Moines, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
Mercy Medical Center-West Lakes
West Des Moines, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-956-4132
Mary Greeley Medical Center
Ames, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
Mercy Cancer Center-West Lakes
Clive, Iowa
This research site can be reached directly by phone. Call to ask about this study.
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- Call 515-241-3305
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa
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- Call 515-241-3305
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa
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- I'm interested
The University of Kansas Cancer Center - Olathe
Olathe, Kansas
- I'm interested
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas
- I'm interested
University of Kansas Cancer Center
Kansas City, Kansas
- Call 785-295-8000
University of Kansas Health System Saint Francis Campus
Topeka, Kansas
This research site can be reached directly by phone. Call to ask about this study.
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University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas
- I'm interested
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas
- I'm interested
Ascension Via Christi Hospitals Wichita
Wichita, Kansas
- I'm interested
Salina Regional Health Center
Salina, Kansas
- I'm interested
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas
- I'm interested
Cancer Center of Kansas - Wichita
Wichita, Kansas
- I'm interested
Cancer Center of Kansas - Salina
Salina, Kansas
- I'm interested
Saint Joseph Hospital
Lexington, Kentucky
- I'm interested
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky
- Call 859-257-3379
University of Kentucky/Markey Cancer Center
Lexington, Kentucky
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Saint Joseph Hospital East
Lexington, Kentucky
- I'm interested
LSU Health Sciences Center at Shreveport
Shreveport, Louisiana
- I'm interested
University Medical Center New Orleans
New Orleans, Louisiana
- I'm interested
Ochsner Medical Center Jefferson
New Orleans, Louisiana
- I'm interested
Louisiana State University Health Science Center
New Orleans, Louisiana
- Call 318-813-1406
Ochsner LSU Health - Cancer Treatment Center
Shreveport, Louisiana
This research site can be reached directly by phone. Call to ask about this study.
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- Call 800-987-3005
Lafayette Family Cancer Center-EMMC
Brewer, Maine
This research site can be reached directly by phone. Call to ask about this study.
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- Call 443-546-1300
Central Maryland Radiation Oncology in Howard County
Columbia, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- Call 800-888-8823
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland
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- I'm interested
University of Maryland Shore Medical Center at Easton
Easton, Maryland
- Call 443-643-3010
UM Upper Chesapeake Medical Center
Bel Air, Maryland
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UM Saint Joseph Medical Center
Towson, Maryland
- I'm interested
UM Capital Region Medical Center
Largo, Maryland
- Call 410-553-8100
UM Baltimore Washington Medical Center/Tate Cancer Center
Glen Burnie, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
TidalHealth Richard A Henson Cancer Institute
Ocean Pines, Maryland
- I'm interested
TidalHealth Peninsula Regional
Salisbury, Maryland
- Call 443-849-3706
Greater Baltimore Medical Center
Baltimore, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Kaiser Permanente - Largo Medical Center
Largo, Maryland
- I'm interested
Kaiser Permanente Lutherville - Timonium Medical Center
Lutherville, Maryland
- Call 410-368-2910
Saint Agnes Hospital
Baltimore, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- Call 443-777-7364
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland
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MedStar Good Samaritan Hospital
Baltimore, Maryland
- I'm interested
MedStar Health Bel Air Medical Campus
Bel Air, Maryland
- I'm interested
Henry Ford Wyandotte Hospital
Wyandotte, Michigan
- I'm interested
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan
- I'm interested
Henry Ford Medical Center-Fairlane
Dearborn, Michigan
- I'm interested
Henry Ford Medical Center-Columbus
Novi, Michigan
- I'm interested
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan
- I'm interested
McLaren Cancer Institute-Bay City
Bay City, Michigan
- I'm interested
McLaren Cancer Institute-Central Michigan
Mount Pleasant, Michigan
- I'm interested
McLaren Cancer Institute-Clarkston
Clarkston, Michigan
- I'm interested
McLaren Cancer Institute-Flint
Flint, Michigan
- I'm interested
McLaren Cancer Institute-Lapeer Region
Lapeer, Michigan
- I'm interested
McLaren Cancer Institute-Macomb
Mount Clemens, Michigan
- I'm interested
McLaren Cancer Institute-Northern Michigan
Petoskey, Michigan
- I'm interested
McLaren-Port Huron
Port Huron, Michigan
- I'm interested
Henry Ford Hospital
Detroit, Michigan
- I'm interested
Henry Ford Health Warren Hospital
Warren, Michigan
- I'm interested
Henry Ford Health Saint John Hospital
Detroit, Michigan
- I'm interested
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan
- I'm interested
Genesys Hurley Cancer Institute
Flint, Michigan
- I'm interested
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan
- Call 248-551-7695
Corewell Health William Beaumont University Hospital
Royal Oak, Michigan
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Corewell Health Lakeland Hospitals - Saint Joseph Hospital
Saint Joseph, Michigan
- I'm interested
Michigan Healthcare Professionals Farmington
Farmington Hills, Michigan
- Call 616-391-1230
Corewell Health Lakeland Hospitals - Niles Hospital
Niles, Michigan
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Michigan Healthcare Professionals Macomb
Macomb, Michigan
- I'm interested
Michigan Healthcare Professionals Madison Heights
Madison Heights, Michigan
- I'm interested
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph, Michigan
- I'm interested
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
Grand Rapids, Michigan
- I'm interested
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan
- Call 248-551-7695
Corewell Health Farmington Hills Hospital
Farmington Hills, Michigan
This research site can be reached directly by phone. Call to ask about this study.
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- Call 248-551-7695
Corewell Health Beaumont Troy Hospital
Troy, Michigan
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- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan
- I'm interested
Trinity Health Medical Center - Brighton
Brighton, Michigan
- I'm interested
Trinity Health Medical Center - Canton
Canton, Michigan
- I'm interested
Trinity Health Muskegon Hospital
Muskegon, Michigan
- I'm interested
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan
- I'm interested
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan
- I'm interested
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan
- I'm interested
Chelsea Hospital
Chelsea, Michigan
- I'm interested
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan
- I'm interested
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan
- I'm interested
Bronson Methodist Hospital
Kalamazoo, Michigan
- I'm interested
Bronson Battle Creek
Battle Creek, Michigan
- Call 574-647-7370
Beacon Kalamazoo
Kalamazoo, Michigan
This research site can be reached directly by phone. Call to ask about this study.
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- Call 800-865-1125
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan
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- I'm interested
University of Michigan Health - West
Wyoming, Michigan
- I'm interested
University of Michigan Rogel Cancer Center
Ann Arbor, Michigan
- I'm interested
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan
- I'm interested
Weisberg Cancer Treatment Center
Farmington Hills, Michigan
- I'm interested
West Michigan Cancer Center
Kalamazoo, Michigan
- I'm interested
Allegiance Health
Jackson, Michigan
- I'm interested
Munson Medical Center
Traverse City, Michigan
- I'm interested
MyMichigan Medical Center Saginaw
Saginaw, Michigan
- I'm interested
MyMichigan Medical Center Tawas
Tawas City, Michigan
- I'm interested
Michigan Healthcare Professionals Troy
Troy, Michigan
- I'm interested
Michigan Healthcare Professionals Clarkston
Clarkston, Michigan
- I'm interested
Karmanos Cancer Institute at McLaren Greater Lansing
Lansing, Michigan
- I'm interested
Hurley Medical Center
Flint, Michigan
- I'm interested
Abbott-Northwestern Hospital
Minneapolis, Minnesota
- I'm interested
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota
- I'm interested
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota
- I'm interested
Fairview Southdale Hospital
Edina, Minnesota
- I'm interested
Lakeview Hospital
Stillwater, Minnesota
- Call 855-776-0015
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota
This research site can be reached directly by phone. Call to ask about this study.
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- Call 855-776-0015
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota
This research site can be reached directly by phone. Call to ask about this study.
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- Call 855-776-0015
Mayo Clinic in Rochester
Rochester, Minnesota
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- I'm interested
Mercy Hospital
Coon Rapids, Minnesota
- I'm interested
Minnesota Oncology - Burnsville
Burnsville, Minnesota
- I'm interested
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota
- I'm interested
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota
- I'm interested
Monticello Cancer Center
Monticello, Minnesota
- I'm interested
North Memorial Medical Health Center
Robbinsdale, Minnesota
- I'm interested
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota
- I'm interested
Regions Hospital
Saint Paul, Minnesota
- I'm interested
Ridgeview Medical Center
Waconia, Minnesota
- I'm interested
Saint Francis Regional Medical Center
Shakopee, Minnesota
- I'm interested
United Hospital
Saint Paul, Minnesota
- I'm interested
Gulfport Memorial Hospital
Gulfport, Mississippi
- I'm interested
University of Kansas Cancer Center - North
Kansas City, Missouri
- I'm interested
Heartland Regional Medical Center
Saint Joseph, Missouri
- Call 314-996-5569
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Saint Francis Medical Center
Cape Girardeau, Missouri
- I'm interested
Freeman Health System
Joplin, Missouri
- Call 417-269-4520
CoxHealth South Hospital
Springfield, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Phelps Health Delbert Day Cancer Institute
Rolla, Missouri
- Call 314-996-5569
Parkland Health Center - Farmington
Farmington, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 417-269-4520
Mercy Hospital Springfield
Springfield, Missouri
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- I'm interested
Mercy Hospital South
St Louis, Missouri
- Call 314-251-7066
Mercy Hospital Saint Louis
St Louis, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 573-458-6379
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 314-996-5569
BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri
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- I'm interested
University of Kansas Cancer Center at North Kansas City Hospital
North Kansas City, Missouri
- Call 573-882-7440
MU Health - University Hospital/Ellis Fischel Cancer Center
Columbia, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 314-996-5569
Missouri Baptist Sullivan Hospital
Sullivan, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 314-996-5569
Missouri Baptist Medical Center
St Louis, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 913-588-3671
University of Kansas Cancer Center - Briarcliff
Kansas City, Missouri
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- I'm interested
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri
- I'm interested
Bozeman Health Deaconess Hospital
Bozeman, Montana
- I'm interested
Billings Clinic Cancer Center
Billings, Montana
- I'm interested
Benefis Sletten Cancer Institute
Great Falls, Montana
- I'm interested
Community Medical Center
Missoula, Montana
- I'm interested
University of Nebraska Medical Center
Omaha, Nebraska
- I'm interested
Nebraska Medicine-Bellevue
Bellevue, Nebraska
- I'm interested
Cancer Partners of Nebraska
Lincoln, Nebraska
- Call 402-559-5600
Nebraska Medicine-Village Pointe
Omaha, Nebraska
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
CHI Health Good Samaritan
Kearney, Nebraska
- I'm interested
Summerlin Hospital Medical Center
Las Vegas, Nevada
- I'm interested
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada
- I'm interested
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada
- I'm interested
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada
- I'm interested
OptumCare Cancer Care at Charleston
Las Vegas, Nevada
- I'm interested
Renown Regional Medical Center
Reno, Nevada
- I'm interested
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada
- I'm interested
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada
- I'm interested
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada
- I'm interested
OptumCare Cancer Care at Seven Hills
Henderson, Nevada
- I'm interested
OptumCare Cancer Care at MountainView
Las Vegas, Nevada
- I'm interested
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire
- Call 201-833-6312
Holy Name Hospital
Teaneck, New Jersey
This research site can be reached directly by phone. Call to ask about this study.
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- Call 973-971-5900
Morristown Medical Center
Morristown, New Jersey
This research site can be reached directly by phone. Call to ask about this study.
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- Call 212-639-7592
Memorial Sloan Kettering Monmouth
Middletown, New Jersey
This research site can be reached directly by phone. Call to ask about this study.
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- Call 212-639-7592
Memorial Sloan Kettering Bergen
Montvale, New Jersey
This research site can be reached directly by phone. Call to ask about this study.
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- Call 212-639-7592
Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey
This research site can be reached directly by phone. Call to ask about this study.
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- Call 908-522-2043
Overlook Hospital
Summit, New Jersey
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- I'm interested
Capital Health Medical Center-Hopewell
Pennington, New Jersey
- Call 973-971-5990
Chilton Medical Center
Pompton, New Jersey
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- I'm interested
University of New Mexico Cancer Center
Albuquerque, New Mexico
- Call 212-639-7592
Memorial Sloan Kettering Commack
Commack, New York
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NYU Langone Hospital - Long Island
Mineola, New York
- I'm interested
NYU Langone Hospital - Brooklyn
Brooklyn, New York
- I'm interested
Mount Sinai Hospital
New York, New York
- I'm interested
Mount Sinai West
New York, New York
- Call 607-798-5230
Lourdes Hospital
Binghamton, New York
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- I'm interested
Mount Sinai Union Square
New York, New York
- I'm interested
Mount Sinai Queens
Astoria, New York
- Call 212-639-7592
Memorial Sloan Kettering Nassau
Uniondale, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 212-639-7592
Memorial Sloan Kettering Westchester
Harrison, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 585-341-8113
Highland Hospital
Rochester, New York
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- I'm interested
Upstate Cancer Center at Oswego
Oswego, New York
- I'm interested
Mary Imogene Bassett Hospital
Cooperstown, New York
- I'm interested
Upstate Cancer Center at Verona
Verona, New York
- I'm interested
Mount Sinai Chelsea
New York, New York
- I'm interested
Upstate Cancer Center Radiation Oncology at Oswego
Oswego, New York
- Call 516-734-8896
Northwell Health/Center for Advanced Medicine
Lake Success, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 516-734-8896
Northwell Health Imbert Cancer Center
Bay Shore, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 516-734-8896
Northwell Health Cancer Institute at Huntington
Greenlawn, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 914-366-1600
Phelps Memorial Hospital Center
Sleepy Hollow, New York
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- I'm interested
Wilmot Cancer Institute at Webster
Webster, New York
- I'm interested
The Cancer Institute at Saint Francis Hospital
East Hills, New York
- I'm interested
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York
- I'm interested
Pluta Cancer Center
Rochester, New York
- I'm interested
Northern Westchester Hospital
Mount Kisco, New York
- Call 315-464-5476
SUNY Upstate Medical Center-Community Campus
Syracuse, New York
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- I'm interested
Roswell Park Cancer Institute
Buffalo, New York
- Call 800-862-2215
Stony Brook University Medical Center
Stony Brook, New York
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- Call 718-226-8888
Staten Island University Hospital
Staten Island, New York
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- Call 315-464-5476
State University of New York Upstate Medical University
Syracuse, New York
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- Call 516-734-8896
Lenox Hill Hospital
New York, New York
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- Call 518-926-6700
Glens Falls Hospital
Glens Falls, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 585-758-7877
Wilmot Cancer Institute Radiation Oncology at Greece
Rochester, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 585-396-6161
Sands Cancer Center
Canandaigua, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 315-472-7504
Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York
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- Call 212-434-4460
Manhattan Eye Ear and Throat Hospital
New York, New York
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- Call 585-275-5830
University of Rochester
Rochester, New York
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- Call 315-472-7504
Hematology Oncology Associates of CNY at Camillus
Camillus, New York
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- Call 212-639-7592
Memorial Sloan Kettering Cancer Center
New York, New York
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- I'm interested
Upstate Cancer Center at Hill Radiation Oncology
Syracuse, New York
- I'm interested
Novant Health Cancer Institute - Wilkesboro
North Wilkesboro, North Carolina
- I'm interested
Mission Hospital
Asheville, North Carolina
- I'm interested
Novant Health Cancer Institute - Huntersville
Huntersville, North Carolina
- I'm interested
Novant Health Cancer Institute - Kernersville
Kernersville, North Carolina
- I'm interested
Novant Health Cancer Institute - Matthews
Matthews, North Carolina
- I'm interested
Novant Health Cancer Institute - Mooresville
Mooresville, North Carolina
- I'm interested
Novant Health Cancer Institute - Mount Airy
Mount Airy, North Carolina
- I'm interested
Novant Health Cancer Institute - Rowan
Salisbury, North Carolina
- I'm interested
Novant Health Cancer Institute - Statesville
Statesville, North Carolina
- I'm interested
Novant Health Cancer Institute - Thomasville
Thomasville, North Carolina
- I'm interested
Novant Health Forsyth Medical Center
Winston-Salem, North Carolina
- I'm interested
Novant Health Presbyterian Medical Center
Charlotte, North Carolina
- I'm interested
Matthews Radiation Oncology Center
Matthews, North Carolina
- I'm interested
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina
- Call 980-442-2000
Levine Cancer Institute-SouthPark
Charlotte, North Carolina
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- Call 800-804-9376
Levine Cancer Institute-Ballantyne
Charlotte, North Carolina
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- Call 980-442-0600
Levine Cancer Institute - Union West
Matthews, North Carolina
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- Call 800-804-9376
Levine Cancer Institute - Rutherford
Forest City, North Carolina
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Rowan Regional Medical Center
Salisbury, North Carolina
- I'm interested
Hope Women's Cancer Centers-Asheville
Asheville, North Carolina
- Call 336-802-2500
Hayworth Cancer Center
High Point, North Carolina
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East Carolina University
Greenville, North Carolina
- Call 800-804-9376
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina
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CarolinaEast Medical Center
New Bern, North Carolina
- Call 800-804-9376
Atrium Health University City/LCI-University
Charlotte, North Carolina
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- Call 980-442-2000
Atrium Health Union/LCI-Union
Monroe, North Carolina
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- Call 800-804-9376
Atrium Health Stanly/LCI-Albemarle
Albemarle, North Carolina
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- Call 980-442-2000
Atrium Health Pineville/LCI-Pineville
Charlotte, North Carolina
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- Call 800-804-9376
Atrium Health Cleveland/LCI-Cleveland
Shelby, North Carolina
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- Call 800-804-9376
Atrium Health Cabarrus/LCI-Concord
Concord, North Carolina
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- Call 888-716-9259
Wake Forest University at Clemmons
Clemmons, North Carolina
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- Call 336-713-6771
Wake Forest University Health Sciences
Winston-Salem, North Carolina
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- Call 701-780-6520
Altru Cancer Center
Grand Forks, North Dakota
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- I'm interested
Kettering Medical Center
Kettering, Ohio
- I'm interested
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio
- I'm interested
Cleveland Clinic Cancer Center Strongsville
Strongsville, Ohio
- I'm interested
Miami Valley Hospital North
Dayton, Ohio
- Call 937-569-7515
Miami Valley Cancer Care and Infusion
Greenville, Ohio
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- I'm interested
MetroHealth Medical Center
Cleveland, Ohio
- I'm interested
Riverside Methodist Hospital
Columbus, Ohio
- I'm interested
Mount Carmel New Albany Surgical Hospital
New Albany, Ohio
- I'm interested
Ohio State University Comprehensive Cancer Center
Columbus, Ohio
- I'm interested
Upper Valley Medical Center
Troy, Ohio
- I'm interested
Miami Valley Hospital South
Centerville, Ohio
- I'm interested
Mount Carmel Health Center West
Columbus, Ohio
- I'm interested
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio
- I'm interested
OhioHealth Mansfield Hospital
Mansfield, Ohio
- I'm interested
OhioHealth Marion General Hospital
Marion, Ohio
- I'm interested
Mount Carmel Grove City Hospital
Grove City, Ohio
- I'm interested
Mount Carmel East Hospital
Columbus, Ohio
- I'm interested
Greater Dayton Cancer Center
Kettering, Ohio
- I'm interested
Grant Medical Center
Columbus, Ohio
- I'm interested
Grady Memorial Hospital
Delaware, Ohio
- I'm interested
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio
- I'm interested
ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital
Toledo, Ohio
- I'm interested
ProMedica Flower Hospital
Sylvania, Ohio
- I'm interested
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio
- I'm interested
Summa Health Medina Medical Center
Medina, Ohio
- I'm interested
Summa Health System - Akron Campus
Akron, Ohio
- I'm interested
Summa Health System - Barberton Campus
Barberton, Ohio
- I'm interested
Aultman Health Foundation
Canton, Ohio
- Call 937-276-8320
Premier Blood and Cancer Center
Dayton, Ohio
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University of Cincinnati Cancer Center-West Chester
West Chester, Ohio
- I'm interested
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio
- I'm interested
University Hospitals Portage Medical Center
Ravenna, Ohio
- I'm interested
University Hospitals Parma Medical Center
Parma, Ohio
- I'm interested
Blanchard Valley Hospital
Findlay, Ohio
- I'm interested
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio
- I'm interested
Armes Family Cancer Center
Findlay, Ohio
- I'm interested
UH Seidman Cancer Center at Southwest General Hospital
Middleburg Heights, Ohio
- I'm interested
Dublin Methodist Hospital
Dublin, Ohio
- I'm interested
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio
- I'm interested
UH Seidman Cancer Center at Firelands Regional Medical Center
Sandusky, Ohio
- I'm interested
Doctors Hospital
Columbus, Ohio
- I'm interested
Delaware Health Center-Grady Cancer Center
Delaware, Ohio
- I'm interested
Miami Valley Hospital
Dayton, Ohio
- I'm interested
Dayton Physicians LLC-Atrium
Franklin, Ohio
- I'm interested
Case Western Reserve University
Cleveland, Ohio
- I'm interested
Dayton Physician LLC - Englewood
Dayton, Ohio
- I'm interested
Cleveland Clinic Akron General
Akron, Ohio
- I'm interested
Cleveland Clinic Cancer Center Mansfield
Mansfield, Ohio
- I'm interested
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio
- Call 888-293-4673
Cleveland Clinic Mercy Hospital
Canton, Ohio
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Indu and Raj Soin Medical Center
Beavercreek, Ohio
- Call 405-752-3402
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma
- Call 503-413-1742
Legacy Meridian Park Hospital
Tualatin, Oregon
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Providence Portland Medical Center
Portland, Oregon
- Call 503-413-2150
Legacy Mount Hood Medical Center
Gresham, Oregon
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Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon
- I'm interested
Clackamas Radiation Oncology Center
Clackamas, Oregon
- I'm interested
Providence Newberg Medical Center
Newberg, Oregon
- I'm interested
Providence Saint Vincent Medical Center
Portland, Oregon
- I'm interested
Providence Willamette Falls Medical Center
Oregon City, Oregon
- Call 412-858-7746
Forbes Hospital
Monroeville, Pennsylvania
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Asplundh Cancer Pavilion
Willow Grove, Pennsylvania
- I'm interested
Geisinger Medical Center
Danville, Pennsylvania
- Call 717-721-4840
Ephrata Cancer Center
Ephrata, Pennsylvania
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- Call 610-237-4982
Mercy Fitzgerald Hospital
Darby, Pennsylvania
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Temple University Hospital
Philadelphia, Pennsylvania
- I'm interested
Chambersburg Hospital
Chambersburg, Pennsylvania
- I'm interested
Sechler Family Cancer Center
Lebanon, Pennsylvania
- I'm interested
Allegheny Valley Hospital
Natrona Heights, Pennsylvania
- I'm interested
Geisinger Cancer Services-Pottsville
Pottsville, Pennsylvania
- I'm interested
Jefferson Torresdale Hospital
Philadelphia, Pennsylvania
- I'm interested
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania
- I'm interested
Fox Chase Cancer Center
Philadelphia, Pennsylvania
- I'm interested
Wexford Health and Wellness Pavilion
Wexford, Pennsylvania
- I'm interested
Jefferson Hospital
Jefferson Hills, Pennsylvania
- Call 800-836-0388
Guthrie Medical Group PC-Robert Packer Hospital
Sayre, Pennsylvania
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Fox Chase Cancer Center - East Norriton Hospital Outpatient Center
East Norriton, Pennsylvania
- Call 215-794-2700
Fox Chase Cancer Center Buckingham
Furlong, Pennsylvania
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Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania
- I'm interested
Yolanda G Barco Oncology Institute
Meadville, Pennsylvania
- I'm interested
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania
- Call 877-284-2000
Allegheny General Hospital
Pittsburgh, Pennsylvania
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- Call 412-578-5000
West Penn Hospital
Pittsburgh, Pennsylvania
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- Call 877-441-7957
WellSpan Health-York Hospital
York, Pennsylvania
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- Call 877-441-7957
WellSpan Health-York Cancer Center
York, Pennsylvania
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Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania
- Call 877-441-7957
Adams Cancer Center
Gettysburg, Pennsylvania
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- Call 814-452-5000
Saint Vincent Hospital
Erie, Pennsylvania
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- Call 888-808-6762
Northeast Radiation Oncology Center
Dunmore, Pennsylvania
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- Call 401-737-7010
Kent Hospital
Warwick, Rhode Island
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- Call 401-444-1488
Rhode Island Hospital
Providence, Rhode Island
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Smilow Cancer Hospital Care Center - Westerly
Westerly, Rhode Island
- Call 401-274-1122
Women and Infants Hospital
Providence, Rhode Island
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- Call 800-804-9376
Rock Hill Radiation Therapy Center
Rock Hill, South Carolina
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McLeod Regional Medical Center
Florence, South Carolina
- Call 800-804-9376
Levine Cancer Institute-Rock Hill
Rock Hill, South Carolina
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Saint Joseph's/Candler - Bluffton Campus
Bluffton, South Carolina
- I'm interested
The Radiation Oncology Center-Hilton Head/Bluffton
Hilton Head Island, South Carolina
- I'm interested
Medical University of South Carolina
Charleston, South Carolina
- I'm interested
Tidelands Georgetown Memorial Hospital
Georgetown, South Carolina
- Call 843-273-7980
Beaufort Memorial/New River Cancer Center
Okatie, South Carolina
This research site can be reached directly by phone. Call to ask about this study.
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- Call 615-342-1919
The Children's Hospital at TriStar Centennial
Nashville, Tennessee
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- Call 865-544-9773
University of Tennessee - Knoxville
Knoxville, Tennessee
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- Call 800-811-8480
Vanderbilt Breast Center at One Hundred Oaks
Nashville, Tennessee
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- Call 800-811-8480
Vanderbilt University/Ingram Cancer Center
Nashville, Tennessee
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MD Anderson League City
League City, Texas
- I'm interested
Houston Methodist San Jacinto Hospital
Baytown, Texas
- Call 806-775-8590
UMC Cancer Center / UMC Health System
Lubbock, Texas
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Houston Methodist Saint John Hospital
Nassau Bay, Texas
- I'm interested
MD Anderson West Houston
Houston, Texas
- Call 832.522.6070
Houston Methodist West Hospital
Houston, Texas
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Houston Methodist The Woodlands Hospital
The Woodlands, Texas
- Call 281.274.7000
Houston Methodist Sugar Land Hospital
Sugar Land, Texas
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M D Anderson Cancer Center
Houston, Texas
- Call 806-775-8590
Texas Tech University Health Sciences Center-Lubbock
Lubbock, Texas
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Methodist Willowbrook Hospital
Houston, Texas
- I'm interested
University of Texas Medical Branch
Galveston, Texas
- I'm interested
Houston Methodist Cypress Hospital
Cypress, Texas
- Call 713.790.3311
Houston Methodist Hospital
Houston, Texas
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- I'm interested
MD Anderson in Sugar Land
Sugar Land, Texas
- I'm interested
MD Anderson in The Woodlands
Conroe, Texas
- I'm interested
Intermountain Medical Center
Murray, Utah
- I'm interested
Logan Regional Hospital
Logan, Utah
- I'm interested
LDS Hospital
Salt Lake City, Utah
- I'm interested
McKay-Dee Hospital Center
Ogden, Utah
- I'm interested
Riverton Hospital
Riverton, Utah
- I'm interested
Saint George Regional Medical Center
St. George, Utah
- I'm interested
Utah Valley Regional Medical Center
Provo, Utah
- I'm interested
Utah Cancer Specialists-Salt Lake City
Salt Lake City, Utah
- I'm interested
Sandra L Maxwell Cancer Center
Cedar City, Utah
- I'm interested
American Fork Hospital / Huntsman Intermountain Cancer Center
American Fork, Utah
- I'm interested
University of Vermont Medical Center
Burlington, Vermont
- I'm interested
University of Vermont and State Agricultural College
Burlington, Vermont
- I'm interested
Dartmouth Cancer Center - North
Saint Johnsbury, Vermont
- I'm interested
Bon Secours Cancer Institute at Reynolds Crossing
Richmond, Virginia
- I'm interested
Bon Secours Memorial Regional Medical Center
Mechanicsville, Virginia
- I'm interested
Bon Secours Saint Francis Medical Center
Midlothian, Virginia
- I'm interested
Bon Secours Saint Mary's Hospital
Richmond, Virginia
- I'm interested
VCU Community Memorial Health Center
South Hill, Virginia
- I'm interested
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington
- I'm interested
Swedish Medical Center-First Hill
Seattle, Washington
- I'm interested
Swedish Medical Center-Ballard Campus
Seattle, Washington
- I'm interested
Swedish Cancer Institute-Issaquah
Issaquah, Washington
- I'm interested
Swedish Cancer Institute-Edmonds
Edmonds, Washington
- I'm interested
Skagit Regional Health Cancer Care Center
Mount Vernon, Washington
- I'm interested
Saint Michael Cancer Center
Silverdale, Washington
- I'm interested
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington
- Call 503-413-2150
Legacy Salmon Creek Hospital
Vancouver, Washington
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- I'm interested
Edwards Comprehensive Cancer Center
Huntington, West Virginia
- I'm interested
Aurora BayCare Medical Center
Green Bay, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - Johnson Creek
Johnson Creek, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin
- I'm interested
Aurora Cancer Care-Grafton
Grafton, Wisconsin
- I'm interested
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin
- I'm interested
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin
- I'm interested
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin
- Call 414-805-0505
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, Wisconsin
This research site can be reached directly by phone. Call to ask about this study.
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- Call 414-805-3666
Medical College of Wisconsin
Milwaukee, Wisconsin
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Aurora Cancer Care-Racine
Racine, Wisconsin
- Call 262-257-5100
Froedtert Menomonee Falls Hospital
Menomonee Falls, Wisconsin
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- I'm interested
Marshfield Medical Center - Minocqua
Minocqua, Wisconsin
- I'm interested
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin
- Call 877-405-6866
Aspirus Regional Cancer Center
Wausau, Wisconsin
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Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin
- I'm interested
Aurora Health Care Germantown Health Center
Germantown, Wisconsin
- I'm interested
Aurora Health Center-Fond du Lac
Fond du Lac, Wisconsin
- I'm interested
Aurora Medical Center in Summit
Summit, Wisconsin
- I'm interested
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin
- I'm interested
Aurora Sinai Medical Center
Milwaukee, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin
- I'm interested
Aurora West Allis Medical Center
West Allis, Wisconsin
- I'm interested
Cancer Center of Western Wisconsin
New Richmond, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin
- I'm interested
Aspirus Medford Hospital
Medford, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin
- Call 715-422-7718
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin
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Aspirus Cancer Care - Stevens Point
Stevens Point, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Sheboygan
Sheboygan, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin
- I'm interested
Aspirus Cancer Care - James Beck Cancer Center
Rhinelander, Wisconsin
- I'm interested
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin
- I'm interested
Marshfield Medical Center - Weston
Weston, Wisconsin
- Call 414-805-0505
Drexel Town Square Health Center
Oak Creek, Wisconsin
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- Call 855-776-0015
Mayo Clinic Health System-Franciscan Healthcare
La Crosse, Wisconsin
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Marshfield Medical Center-Marshfield
Marshfield, Wisconsin
- I'm interested
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin
- I'm interested
Langlade Hospital and Cancer Center
Antigo, Wisconsin
- I'm interested
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin
- I'm interested
Sheboygan Physicians Group
Sheboygan, Wisconsin
- Call 262-928-7878
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin
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Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin
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ProHealth D N Greenwald Center
Mukwonago, Wisconsin
Who can participate
Inclusion criteria
- ✓The patient or a legally authorized representative must provide study-specific informed consent prior to pre-entry/Step 1 and, for patients treated in the U.S., authorization permitting release of personal health information.
- ✓The patient must have an ECOG performance status of 0 or 1.
- ✓The patient must have undergone a lumpectomy and the margins of the resected specimen or re-excision must be histologically free of invasive tumor and DCIS with no ink on tumor as determined by the local pathologist. If pathologic examination demonstrates tumor at the line of resection, additional excisions may be performed to obtain clear margins. (Patients with margins positive for LCIS are eligible without additional resection.)
- ✓The tumor must be unilateral invasive adenocarcinoma of the breast on histologic examination.
- ✓Patient must have undergone axillary staging (sentinel node biopsy and/or axillary node dissection).
- ✓The following staging criteria must be met postoperatively according to AJCC 8th edition criteria:
- ✓By pathologic evaluation, primary tumor must be pT1 (less than or equal to 2 cm).
- ✓By pathologic evaluation, ipsilateral nodes must be pN0. (Patients with pathologic staging of pN0(i+) or pN0(mol+) are NOT eligible.)
- ✓Oncotype DX Recurrence Score of less than or equal to 18 on diagnostic core biopsy or resected specimen.
- ✓\*\* For patients with a T1a tumor (less than or equal to 0.5 cm in size) or patients at Canadian provinces or approved international sites where Oncotype DX Recurrence Score testing would not be covered, who do not already have an Oncotype DX Recurrence Score at pre-entry/Step 1, a specimen (unstained blocks or slides) must be sent to the Genomic Health centralized laboratory. Tumor size sample must be greater than or equal to 0.2 cm for analysis.
- ✓\*\*\* The Oncotype RS can be run on the biopsy core or surgical specimen. The patient cannot have initiated endocrine therapy prior to tissue collection.
- ✓An Oncotype RS is required for eligibility, however, for a patient whose tumor has already had a MammaPrint test completed as part of usual care when being considered for enrollment and is in the binary "Low" category will meet this eligibility criteria and an Oncotype RS does not need to be performed.
- ✓The tumor must have been determined to be ER and/or PgR positive assessed by current ASCO/CAP Guideline Recommendations for hormone receptor testing. Patients with greater than or equal to 1% ER or PgR staining by IHC are considered positive.
- ✓The tumor must have been determined to be HER2-negative by current ASCO/CAP guidelines.
- ✓Patients may be premenopausal or postmenopausal at the time of pre-entry/Step 1. For study purposes, postmenopausal is defined as:
- ✓Age 56 or older with no spontaneous menses for at least 12 months prior to pre-entry/Step 1; or a documented hysterectomy; or
- ✓Age 55 or younger with no spontaneous menses for at least 12 months prior to pre-entry/Step 1 (e.g., spontaneous or secondary to hysterectomy) and with a documented estradiol level in the postmenopausal range according to local institutional/laboratory standard; or Documented bilateral oophorectomy.
- ✓The interval between the last surgery for breast cancer (including re-excision of margins) and pre-entry/Step 1 must be no more than 70 days.
- ✓The patient must have recovered from surgery with the incision completely healed and no signs of infection.
- ✓Bilateral mammogram or MRI within 6 months prior to pre-entry/Step 1. HIV-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial. Patients must be intending to take endocrine therapy for a minimum 5 years duration (tamoxifen or aromatase inhibitor). The specific regimen of endocrine therapy is at the treating physician's discretion.
Exclusion criteria
- ✕Definitive clinical or radiologic evidence of metastatic disease.
- ✕pT1 mi and pT2 - pT4 tumors including inflammatory breast cancer.
- ✕Pathologic staging of pN0(i+) or pN0(mol+), pN1, pN2, or pN3 disease.
- ✕Patient had a mastectomy.
- ✕Palpable or radiographically suspicious ipsilateral or contralateral axillary, supraclavicular, infraclavicular, or internal mammary nodes, unless there is histologic confirmation that these nodes are negative for tumor.
- ✕Suspicious microcalcifications, densities, or palpable abnormalities (in the ipsilateral or contralateral breast) unless biopsied and found to be benign.
- ✕Non-epithelial breast malignancies such as sarcoma or lymphoma.
- ✕Proven multicentric carcinoma (invasive cancer or DCIS) in more than one quadrant or separated by 4 or more centimeters. (Patients with multifocal carcinoma are eligible.)
- ✕Paget's disease of the nipple.
- ✕Any history, not including the index cancer, of ipsilateral invasive breast cancer or ipsilateral DCIS treated or not treated. (Patients with synchronous or previous ipsilateral LCIS are eligible.)
- ✕Synchronous or previous contralateral invasive breast cancer or DCIS. (Patients with synchronous and/or previous contralateral LCIS are eligible.)
- ✕Surgical margins that cannot be microscopically assessed or are positive at pathologic evaluation. (If surgical margins are rendered free of disease by re- excision, the patient is eligible.)
- ✕Treatment plan that includes regional nodal irradiation.
- ✕Any treatment with radiation therapy, chemotherapy, or biotherapy, administered for the currently diagnosed breast cancer prior to pre-entry/Step 1.
- ✕History of non-breast malignancies (except for in situ cancers treated only by local excision and basal cell and squamous cell carcinomas of the skin) within 5 years prior to pre-entry/Step 1.
- ✕Current therapy with any endocrine therapy such as raloxifene (Evista®), tamoxifen, or other selective estrogen receptor modulators (SERMs), either for osteoporosis or breast cancer prevention.
- ✕\*\* Patients are eligible for BR007 if they receive a short course of preoperative endocrine therapy of less than 6 weeks duration (prior to randomization/Step 2) for this diagnosis after the core biopsy (and can continue postoperatively if:
- ✕the Oncotype DX Recurrence Score is assessed on the biopsy core and is less than or equal to 18, AND
- ✕the patient had not initiated endocrine therapy prior to core biopsy tissue collection.
- ✕\*\*\* This does not apply to adjuvant endocrine therapy recommended for this diagnosis which may start any time after surgery including prior to registration (Pre-entry/Step 1).
- ✕Patients intending to continue on oral, transdermal, or subdermal estrogen replacement (including all estrogen only and estrogen-progesterone formulas) are not eligible. Patients that discontinue oral, transdermal, or subdermal estrogen replacement prior to registration are eligible.
- ✕Prior breast or thoracic RT for any condition.
- ✕Active collagen vascular disease, specifically dermatomyositis with a CPK level above normal or with an active skin rash, systemic lupus erythematosis, or scleroderma.
- ✕Pregnancy or lactation at the time of pre-entry/Step 1 or intention to become pregnant during treatment. (Note: Pregnancy testing according to institutional standards for women of childbearing potential must be performed within 2 weeks prior to pre-entry/Step 1.)
- ✕Any other disease, metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion of a disease or condition that contraindicates the use of study therapy or that may affect the interpretation of the results or render the patient at high risk from treatment complications.
- ✕Psychiatric or addictive disorders or other conditions that, in the opinion of the investigator, would preclude the patient from meeting the study requirements or interfere with interpretation of study results.
- ✕Use of any investigational product within 30 days prior to pre-entry/Step 1.
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.