Effects of Spirulina Supplementation on Mental Health in Healthy Adults
Sponsored by Arizona State University
About this study
Spirulina platensis is a form of cyanobacteria, a blue-green algae, and is a superfood most known for being rich in protein, vitamins and minerals, and healthful phytochemicals. Spirulina supports brain health through neuroprotection offered by its antioxidants, anti-inflammatory properties, and hormone regulation. The aim of this study is to supplement healthy adults from a campus community with 3g of spirulina, daily, for 8 weeks to improve mood and mental acuity in comparison to receiving a placebo.
Spirulina is nutrient-dense with vitamins and minerals which provide antioxidants and anti-inflammatory mechanisms to help reduce oxidative stress and ROS activity. Preclinical studies have indicated Spirulina can reduce inflammatory cytokines, such as IL-1β, and reverse stress responses and oxidative damage in BDNF, nuclear factor erythroid 2-related factor (NRF2), and ultimately the phosphorylation of protein-kinase B (AKT), which promotes cell growth. In addition to these benefits, fatty acids, gamma-linolenic acid (GLA) and glycolipids, support gut health and the immune system. In combination, all these nutrients help increase neuroprotection and brain health. It is evident that Spirulina supports brain health through neuroprotection, antioxidants, anti-inflammatory properties, and ho…
Where this study is enrolling
- I'm interested
850 PBC
Phoenix, Arizona
Who can participate
Inclusion criteria
- ✓healthy adults
- ✓ages 18-65
- ✓no underlying chronic disease or acute conditions
- ✓no autoimmune conditions
- ✓do not consume alcohol in excess, smoke, use recreational drugs
- ✓does not follow restrictive diets
- ✓will be recruited from the ASU university campus.
Exclusion criteria
- ✕not have been clinically diagnosed with depression
- ✕not taking antidepressants, anxiety, or stress medications, or any other medications
- ✕drugs, or supplements that could influence mental capacities
- ✕not pregnant or breastfeeding
- ✕not a competitive athlete
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.