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Error-enhanced Learning & Recovery in 2 & 3 Dimensions

Sponsored by Shirley Ryan AbilityLab

About this study

This study is being done to see how errors lead to improvement. Specifically, we are evaluating the errors stroke participants make during an upper extremity exercise program when reaching for a target using their affected arm. Once we understand the participant's reaching errors, we plan to create a customized reaching exercise according to the individual's specific error tendencies which will lead to better performance on movement ability after training.

The neuroplasticity of motor re-learning is a key pathway for recovery in neurorehabilitation. One critical challenge to devising treatment plans for motor recovery is the wide variation that exists between individuals, across movement repetitions, and even within movements. Development of a learning model that looks at these factors would better relate diagnoses to treatments, providing personalization and efficiency to therapy. This proposal aims to advance rehabilitation by building a modeling framework that explores the trends and exploits a fundamental learning process - error. Our goal is to preliminarily test the direct effect of this new treatment in preparation for the randomized controlled study to come. Understanding how error leads to better performance will help us program fut…

Where this study is enrolling (2)

Who can participate

Inclusion criteria

  • ✓1. 18 years of age or older
  • ✓2. Chronic stroke (8+ months post stroke event) with primary motor cortex involvement
  • ✓3. Hemiparesis
  • ✓4. Some degree of both shoulder and elbow movement capability

Exclusion criteria

  • ✕1. Bilateral paresis
  • ✕2. Severe tactile deficits using the Two-Point Discrimination Test (participant must detect\<11mm)
  • ✕3. Severe proprioceptive deficits
  • ✕4. Severe spasticity (Modified Ashworth \>3) preventing movement
  • ✕5. Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment
  • ✕6. Visual deficits, and hemispatial neglect that would prevent the subjects from seeing the targets.
  • ✕7. Inability to provide an informed consent
  • ✕8. severe current medical problems
  • ✕9. diffuse/multiple lesion sites or multiple stroke events
  • ✕10. Inability to attain and maintain testing positions
  • ✕11. Botox injection to the affected upper extremity within the previous 4 months
  • ✕12. Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy
  • ✕13. Participation in previous, similar robotics intervention study
  • ✕14. Other neurological issues
  • ✕None of the following special populations will be included in this research study:
  • ✕Adults unable to consent
  • ✕Individuals who are not yet adults (infants, children, teenagers)
  • ✕Pregnant women
  • ✕Prisoners
  • ✕Vulnerable Populations

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.