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Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition

Sponsored by University of Chicago

About this study

Most stroke patients are initially evaluated at the closest hospital but some need to be transferred to a hospital that can provide more advanced care. The "Door-In-Door-Out" (DIDO) process at the first hospital can take time making transferred patients no longer able to get the advanced treatments. This study will help hospitals across the US "stand up" new ways to evaluate stroke patients, decide who needs to be transferred, and transfer them quickly for advanced treatment.

Nearly 800,000 people in the United States (US) each year experience acute stroke, which remains the leading cause of adult disability and 5th leading cause of death. Despite the proliferation of stroke centers nationwide, almost half of the US population lives beyond a 60-minute drive of a comprehensive stroke center (CSC) and many patients require inter-hospital transfer (IHT) from a non-CSC to a CSC. Building upon prior work to reduce door-in-door-out (DIDO) time at referring hospitals, this proposal entitled "Hospital Implementation of a Stroke Protocol for Emergency Evaluation and Disposition (HI-SPEED)" study seeks to (1) implement a novel, evidence-based, multi-component DIDO intervention in eight diverse stroke systems of care across multiple regions of the US and (2) conduct a dua…

Where this study is enrolling (8)

Show all 8 locations
Who can participate

Inclusion criteria

  • ✓Age \>=18 years
  • ✓Final diagnosis: AIS, ICH, or SAH

Exclusion criteria

  • ✕Final diagnosis: TIA or stroke NOS
  • ✕Age \<18 years
  • ✕Comfort care measures on day 0 or 1
  • ✕Left hospital against medical advice
  • ✕Enrolled in clinical trial related to stroke that is competing with this study

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Trial data sourced from ClinicalTrials.gov.