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Phase 3Starting soon

Morphine or Ketamine for Analgesia

Sponsored by Columbia University

About this study

Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences. Morphine is the standard treatment for children with moderate to severe acute pain, but its use is associated with serious side effects and caregiver and clinician concerns related to opioid administration. The investigators aim to determine if sub-dissociative ketamine is non-inferior to morphine for treating acute pain and a preferable alternative for treating acute pain in children because of its more favorable side effect profile and potential long-term benefits related to pain-related function, analgesic use/misuse, and mental and behavioral health outcomes.

Enrolling at this location

UPMC Children's Hospital of Pittsburgh

Pittsburgh, Pennsylvania

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This study also enrolls at 7 other locations. See all.

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Trial data sourced from ClinicalTrials.gov.