Neurovascular Transduction During Exercise in Chronic Kidney Disease
Sponsored by Emory University
About this study
The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and to explore what causes an increase in blood pressure during exercise (i.e. increased adrenaline levels, or decreased ability of blood vessels to dilate). This study will also test whether or not regular exercise on a bicycle and/or treatment with 6R-BH4 (Kuvan) pills, or histidine and beta-alanine supplementation improves these measures during exercise. 6R-BH4 is currently FDA-approved for use in patients with certain forms of a disease called phenylketonuria, but it is not currently FDA approved for blood pressure or exercise capacity in people with CKD.
Enrolling at this location
Emory University Hospital Midtown
Atlanta, Georgia
I'm interestedThis study also enrolls at 2 other locations. See all.
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Trial data sourced from ClinicalTrials.gov.