Peanuts for Cardiometabolic, Brain, and Intestinal Health
Sponsored by Georgia State University
About this study
The overall objective of this 14-month randomized crossover study is to seek evidence demonstrating that daily consumption of peanuts and peanut products improve cardiometabolic, cognitive, and intestinal health in a racially diverse prediabetes population.
In the US, 37.1 million adults have diabetes mellitus and 96 million have prediabetes. Type 2 diabetes mellitus (T2DM) accounts for 95% of the cases and results in many public health complications that increase economic burden and reduce productivity and quality of life. Eight out of 10 people with T2DM die from cardiovascular disease, while those with T2DM also face a 50% higher risk of developing dementia compared to healthy individuals. Also, studies indicate that intestinal health significantly influences the development of T2DM. Of note, the burden of T2DM is particularly pronounced in non-Hispanic Black and Hispanic populations compared to the non-Hispanic White population. Prevention and treatment of T2DM focus on lifestyle changes including dietary modifications. Plant-based foods,…
Where this study is enrolling
- I'm interested
Georgia State University
Atlanta, Georgia
Who can participate
Inclusion criteria
- ✓men and women
- ✓20-59 years of age
- ✓BMI: 24.5 - 35.5 kg/m\^2
- ✓Prediabetes (fasting blood glucose levels 100-125 mg/dL and/or HbA1c between 5.7-6.4%)
- ✓Ability to give consent
Exclusion criteria
- ✕Allergies to peanuts and peanut products
- ✕Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs
- ✕Active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological diseases or severe head injury
- ✕Smoking
- ✕Consumes greater than 2 alcoholic beverages per day
- ✕Consumes antioxidant, probiotic, and prebiotic supplements
- ✕Pregnant or Lactating
- ✕Actively participating in a weight loss program
- ✕MRI Exclusion Criteria:
- ✕Certain neurological disorders (e.g., uncontrolled seizure disorders)
- ✕Braces on their teeth, a cardiac pacemaker; hearing aid; other metal in the body or eyes (which may include certain metallic-embedded tattoos), including but not limited to pins, screws, shrapnel, plates, dentures or other metal objects
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.