Back to Clinical Trials
Phase 2Recruiting

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

Sponsored by Bristol-Myers Squibb

About this study

A Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI Therapy

Where this study is enrolling (20)

  • Shaw Cancer Center

    Edwards, Colorado

    Call 970-569-7608

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Piedmont Healthcare

    Atlanta, Georgia

    Call 706-660-6449

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • John B Amos Cancer Center

    Columbus, Georgia

    Call 706-660-6449

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Rush University Medical Center

    Chicago, Illinois

    I'm interested

  • Dana-Farber Cancer Institute

    Boston, Massachusetts

    Call 617-632-6049

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

Show all 20 locations

  • Washington University School of Medicine

    St Louis, Missouri

    Call 314-273-8008

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Renown Regional Medical Center

    Reno, Nevada

    Call 775-985-4000

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Rochester General Hospital Infectious Disease

    Rochester, New York

    Call 585-922-4020

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Weill Cornell Medical College

    New York, New York

    Call 631-745-0359

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    Mineola, New York

    Call 212-731-5662

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • NYU Langone Health

    New York, New York

    Call 212-731-5662

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C

    Columbus, Ohio

    Call 614-688-7567

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio

    Call 301-980-8969

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Providence Cancer Institute Franz Clinic

    Portland, Oregon

    Call 503-215-5696

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Providence St. Vincent Medical Center

    Portland, Oregon

    Call 503-215-5696

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania

    Call 267-438-8154

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • West Penn Allegheny Health

    Pittsburgh, Pennsylvania

    Call 503-494-8426

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Tennessee Oncology

    Nashville, Tennessee

    Call 615-322-4967

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • Virginia Commonwealth University (Vcu)

    Richmond, Virginia

    Call 804-828-7999

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

  • University of Virginia Health System

    Charlottesville, Virginia

    Call 434-924-4251

    This research site can be reached directly by phone. Call to ask about this study.

    Create a free account to get updates on similar Clinical Trials for your conditions.

Who can participate

Inclusion criteria

  • ✓Non-squamous NSCLC, not amenable to treatment in curative intent.
  • ✓Documented evidence of EGFR mutation (exon 19 deletion, L858R mutation).
  • ✓Progressive disease on a 3rd-generation (such as osimertinib, furmonertinib, lazertinib,...) EGFR-TKI-based mono- or combination therapy regimen as the most recent line of therapy in an adjuvant, locally advanced, or metastatic treatment setting.
  • ✓Eligible to receive a platinum-based doublet chemotherapy regimen (either cisplatin or carboplatin in combination with pemetrexed).

Exclusion criteria

  • ✕Inadequate organ function and/or bone marrow reserve.
  • ✕Leptomeningeal metastases or spinal cord compression.
  • ✕Poorly controlled systemic medical conditions.
  • ✕Other protocol-defined inclusion/exclusion criteria apply.

Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.

Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.

Trial data sourced from ClinicalTrials.gov.