Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Sponsored by National Cancer Institute (NCI)
About this study
This phase III ALCHEMIST treatment trial tests the addition of pembrolizumab to usual chemotherapy for the treatment of stage IIA, IIB, IIIA or IIIB non-small cell lung cancer that has been removed by surgery. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as cisplatin, pemetrexed, carboplatin, gemcitabine hydrochloride, and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving pembrolizumab with usual chemotherapy may help increase survival times in patients with stage IIA, IIB, IIIA or IIIB non-small cell lung cancer.
PRIMARY OBJECTIVE: I. To compare the disease free survival (DFS) between Arm B versus (vs) Arm C in patients with stage IIA-IIIB (T3-4N2) non-small cell lung cancer. SECONDARY OBJECTIVES: I. To compare the overall survival (OS) between the two treatment arms in patients with stage IIA-IIIB (T3-4N2) non-small cell lung cancer. II. To compare the adverse event rates and drug discontinuation rates due to adverse events in patients with stage IIA-IIIB (T3-4N2) non-small cell lung cancer. III. To compare the adverse event (AE) rates for Arms B and C with A (prior to Update #7) and estimate the DFS and OS in Arm A. IV. To compare the DFS and OS in patients with stage IIA-IIIB (T3-4N2) non-small cell lung cancer that receive at least 2 cycles of initial adjuvant chemotherapy. QUALITY OF LI…
Where this study is enrolling (621)
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Katmai Oncology Group
Anchorage, Alaska
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Fairbanks Memorial Hospital
Fairbanks, Alaska
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Banner Boswell Medical Center
Sun City, Arizona
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NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro
Jonesboro, Arkansas
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Kaiser Permanente-Richmond
Richmond, California
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California Pacific Medical Center-Pacific Campus
San Francisco, California
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Kaiser Permanente-Woodland Hills
Woodland Hills, California
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Palo Alto Medical Foundation Health Care
Palo Alto, California
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Kaiser Permanente-Bellflower
Bellflower, California
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Kaiser Permanente-Walnut Creek
Walnut Creek, California
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Kaiser Permanente-Vallejo
Vallejo, California
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Baldwin Park, California
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Anaheim, California
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Kaiser Permanente West Los Angeles
Los Angeles, California
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Harbor City, California
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Kaiser Permanente San Leandro
San Leandro, California
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Kaiser Permanente - Panorama City
Panorama City, California
- Call 877-642-4691
Kaiser Permanente- Modesto MOB II
Modesto, California
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Fremont, California
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Kaiser Permanente Medical Center-Vacaville
Vacaville, California
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Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California
- Call 909-558-4050
Loma Linda University Medical Center
Loma Linda, California
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- Call 707-967-3698
Saint Helena Hospital
St. Helena, California
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Kaiser Permanente Los Angeles Medical Center
Los Angeles, California
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Kaiser Permanente Fresno Orchard Plaza
Fresno, California
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Dublin, California
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Kaiser Permanente Downtown Commons
Sacramento, California
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John Muir Medical Center-Walnut Creek
Walnut Creek, California
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Fremont - Rideout Cancer Center
Marysville, California
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Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California
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Palo Alto Medical Foundation-Fremont
Fremont, California
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UC San Diego Moores Cancer Center
La Jolla, California
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Kaiser Permanente-Fresno
Fresno, California
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Kaiser Permanente-Fontana
Fontana, California
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Tibor Rubin VA Medical Center
Long Beach, California
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Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California
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Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California
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Kaiser Permanente-Irvine
Irvine, California
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Palo Alto Medical Foundation-Camino Division
Mountain View, California
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University of California Davis Comprehensive Cancer Center
Sacramento, California
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Kaiser Permanente-Stockton
Stockton, California
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Kaiser Permanente-South San Francisco
South San Francisco, California
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Memorial Medical Center
Modesto, California
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Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee, California
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Sacramento, California
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San Jose, California
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Santa Rosa, California
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Kaiser San Rafael-Gallinas
San Rafael, California
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Vallejo, California
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Roseville, California
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Sacramento, California
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San Marcos, California
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San Diego, California
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Roseville, California
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Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California
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Sutter Auburn Faith Hospital
Auburn, California
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Stanford Cancer Institute Palo Alto
Palo Alto, California
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Kaiser Permanente-Deer Valley Medical Center
Antioch, California
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Modesto, California
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Oakland, California
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Ontario, California
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Kaiser Permanente-Riverside
Riverside, California
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Rocky Mountain Cancer Centers-Boulder
Boulder, Colorado
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Rocky Mountain Cancer Centers-Aurora
Aurora, Colorado
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Rocky Mountain Cancer Centers - Swedish
Englewood, Colorado
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Poudre Valley Hospital
Fort Collins, Colorado
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Medical Center of the Rockies
Loveland, Colorado
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Aurora, Colorado
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Colorado Springs, Colorado
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Greeley, Colorado
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Memorial Hospital North
Colorado Springs, Colorado
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Lone Tree, Colorado
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Cancer Care and Hematology-Fort Collins
Fort Collins, Colorado
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Lafayette, Colorado
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National Jewish Health-Main Campus
Denver, Colorado
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Thornton, Colorado
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Golden, Colorado
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Denver, Colorado
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Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut
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Fairfield, Connecticut
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Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut
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Yale University
New Haven, Connecticut
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Smilow Cancer Hospital-Torrington Care Center
Torrington, Connecticut
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Smilow Cancer Hospital-Waterbury Care Center
Waterbury, Connecticut
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Veterans Affairs Connecticut Healthcare System-West Haven Campus
West Haven, Connecticut
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Smilow Cancer Hospital-Derby Care Center
Derby, Connecticut
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Greenwich, Connecticut
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Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut
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Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut
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Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut
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Medical Oncology Hematology Consultants PA
Newark, Delaware
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Beebe South Coastal Health Campus
Millville, Delaware
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Helen F Graham Cancer Center
Newark, Delaware
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Beebe Health Campus
Rehoboth Beach, Delaware
- Call 202-877-8839
MedStar Washington Hospital Center
Washington D.C., District of Columbia
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MedStar Georgetown University Hospital
Washington D.C., District of Columbia
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Kaiser Permanente-Capitol Hill Medical Center
Washington D.C., District of Columbia
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Regional Cancer Center-Lee Memorial Health System
Fort Myers, Florida
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Moffitt Cancer Center
Tampa, Florida
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Mount Sinai Comprehensive Cancer Center at Aventura
Aventura, Florida
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Mount Sinai Medical Center
Miami Beach, Florida
- Call 954-265-4325
Memorial Hospital West
Pembroke Pines, Florida
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Holy Cross Hospital
Fort Lauderdale, Florida
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Malcom Randall Veterans Administration Medical Center
Gainesville, Florida
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Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida
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Moffitt Cancer Center at SouthShore
Ruskin, Florida
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Northeast Georgia Medical Center-Gainesville
Gainesville, Georgia
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Northside Hospital
Atlanta, Georgia
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Northside Hospital - Gwinnett
Lawrenceville, Georgia
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Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
Savannah, Georgia
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Northside Hospital - Duluth
Duluth, Georgia
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Kaiser Permanente Moanalua Medical Center
Honolulu, Hawaii
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Queen's Cancer Cenrer - POB I
Honolulu, Hawaii
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Queen's Cancer Center - Kuakini
Honolulu, Hawaii
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Queen's Medical Center
Honolulu, Hawaii
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Pali Momi Medical Center
‘Aiea, Hawaii
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Hawaii Cancer Care - Westridge
‘Aiea, Hawaii
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Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii
- Call 808-522-4333
Straub Clinic and Hospital
Honolulu, Hawaii
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Saint Luke's Cancer Institute - Boise
Boise, Idaho
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Saint Luke's Cancer Institute - Nampa
Nampa, Idaho
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Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho
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Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho
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Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho
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Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho
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Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho
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Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho
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Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho
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Saint Luke's Cancer Institute - Meridian
Meridian, Idaho
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Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho
- Call 708-226-4357
Loyola University Medical Center
Maywood, Illinois
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UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois
- Call 309-779-2000
Trinity Medical Center
Moline, Illinois
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SSM Health Good Samaritan
Mount Vernon, Illinois
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Springfield Clinic
Springfield, Illinois
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- Call 217-545-7929
Southern Illinois University School of Medicine
Springfield, Illinois
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Advocate Christ Medical Center
Oak Lawn, Illinois
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Advocate Good Samaritan Hospital
Downers Grove, Illinois
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Cancer Care Center of O'Fallon
O'Fallon, Illinois
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Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois
- Call 847-842-4847
Advocate Good Shepherd Hospital
Barrington, Illinois
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Carle at The Riverfront
Danville, Illinois
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Carle Cancer Center
Urbana, Illinois
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Carle Physician Group-Effingham
Effingham, Illinois
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Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois
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SIH Cancer Institute
Carterville, Illinois
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Advocate Illinois Masonic Medical Center
Chicago, Illinois
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Centralia Oncology Clinic
Centralia, Illinois
- Call 847-384-3621
Advocate Lutheran General Hospital
Park Ridge, Illinois
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Rush-Copley Medical Center
Aurora, Illinois
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Advocate Sherman Hospital
Elgin, Illinois
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Condell Memorial Hospital
Libertyville, Illinois
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Advocate South Suburban Hospital
Hazel Crest, Illinois
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Crossroads Cancer Center
Effingham, Illinois
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Decatur Memorial Hospital
Decatur, Illinois
- Call 708-202-8387
Edward Hines Jr VA Hospital
Hines, Illinois
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- Call 815-227-2633
OSF Saint Anthony Medical Center
Rockford, Illinois
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NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois
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NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois
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NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois
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AMG Crystal Lake - Oncology
Crystal Lake, Illinois
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AMG Libertyville - Oncology
Libertyville, Illinois
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UW Health Carbone Cancer Center Rockford
Rockford, Illinois
- Call 312-355-3046
University of Illinois
Chicago, Illinois
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University of Chicago Medicine-Orland Park
Orland Park, Illinois
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois
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Memorial Hospital East
Shiloh, Illinois
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Illinois CancerCare - Washington
Washington, Illinois
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Illinois CancerCare-Bloomington
Bloomington, Illinois
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Illinois CancerCare-Canton
Canton, Illinois
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Illinois CancerCare-Galesburg
Galesburg, Illinois
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Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois
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Illinois CancerCare-Pekin
Pekin, Illinois
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Illinois CancerCare-Peoria
Peoria, Illinois
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Ingalls Memorial Hospital
Harvey, Illinois
- Call (312) 864-0200
John H Stroger Jr Hospital of Cook County
Chicago, Illinois
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Baptist Health Floyd
New Albany, Indiana
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Saint Catherine Hospital
Indianapolis, Indiana
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Saint Mary Medical Center
Hobart, Indiana
- Call 219-947-1795
Northwest Cancer Center - Hobart
Hobart, Indiana
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Northwest Cancer Center - Crown Point
Crown Point, Indiana
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Women's Diagnostic Center - Munster
Munster, Indiana
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Northwest Oncology LLC
Dyer, Indiana
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- Call 877-784-4673
Parkview Regional Medical Center
Fort Wayne, Indiana
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- Call 219-836-3349
The Community Hospital
Munster, Indiana
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Northwest Cancer Center - Valparaiso
Valparaiso, Indiana
- Call 515-241-3305
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa
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Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa
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McFarland Clinic - Ames
Ames, Iowa
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UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa
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Mary Greeley Medical Center
Ames, Iowa
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Physicians' Clinic of Iowa PC
Cedar Rapids, Iowa
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Iowa Methodist Medical Center
Des Moines, Iowa
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Saint Anthony Regional Hospital
Carroll, Iowa
- Call 712-322-4136
Heartland Oncology and Hematology LLP
Council Bluffs, Iowa
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Mercy Medical Center - Des Moines
Des Moines, Iowa
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- Call 515-282-2200
Broadlawns Medical Center
Des Moines, Iowa
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Mercy Hospital
Cedar Rapids, Iowa
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McFarland Clinic - Marshalltown
Marshalltown, Iowa
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McFarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa
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UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa
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UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa
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UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa
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Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas
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Cancer Center of Kansas - Wichita
Wichita, Kansas
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Cancer Center of Kansas - Pratt
Pratt, Kansas
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The University of Kansas Cancer Center - Olathe
Olathe, Kansas
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Ascension Via Christi Hospitals Wichita
Wichita, Kansas
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Baptist Health Louisville
Louisville, Kentucky
- Call 859-257-3379
University of Kentucky/Markey Cancer Center
Lexington, Kentucky
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- Call 270-706-5470
Baptist Health Hardin
Elizabethtown, Kentucky
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- Call 866-213-3025
Baptist Health Hamburg
Lexington, Kentucky
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Baptist Health Lexington
Lexington, Kentucky
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Ochsner Medical Center Kenner
Kenner, Louisiana
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Ochsner Medical Center Jefferson
New Orleans, Louisiana
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Ochsner Hematology Oncology North Shore - Covington (West Region)
Covington, Louisiana
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Louisiana Hematology Oncology Associates LLC
Baton Rouge, Louisiana
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LSU Health Baton Rouge-North Clinic
Baton Rouge, Louisiana
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Touro Infirmary
New Orleans, Louisiana
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University Medical Center New Orleans
New Orleans, Louisiana
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Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana
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Medical Center of Baton Rouge
Baton Rouge, Louisiana
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CHRISTUS Highland Medical Center
Shreveport, Louisiana
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Our Lady of the Lake Physician Group
Baton Rouge, Louisiana
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Northshore Oncology Associates-Covington
Covington, Louisiana
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Terrebonne General Medical Center
Houma, Louisiana
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Penobscot Bay Medical Center
Rockport, Maine
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MaineHealth Cancer Care and IV Therapy - Sanford
Sanford, Maine
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MaineHealth Cancer Care and IV Therapy - South Portland
South Portland, Maine
- Call 207-459-1600
MaineHealth Cancer Care Center of York County
Sanford, Maine
This research site can be reached directly by phone. Call to ask about this study.
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- Call 207-626-4855
Harold Alfond Center for Cancer Care
Augusta, Maine
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- I'm interested
MaineHealth Maine Medical Center- Scarborough
Scarborough, Maine
- I'm interested
MaineHealth Waldo Hospital
Belfast, Maine
- Call 800-987-3005
Lafayette Family Cancer Center-EMMC
Brewer, Maine
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Kaiser Permanente-Gaithersburg Medical Center
Gaithersburg, Maryland
- I'm interested
Kaiser Permanente-Woodlawn Medical Center
Baltimore, Maryland
- Call 443-849-3706
Greater Baltimore Medical Center
Baltimore, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- Call 410-601-9083
Sinai Hospital of Baltimore
Baltimore, Maryland
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- I'm interested
Kaiser Permanente Lutherville - Timonium Medical Center
Lutherville, Maryland
- Call 410-871-6400
William E Kahlert Regional Cancer Center/Sinai Hospital
Westminster, Maryland
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- I'm interested
Luminis Health Anne Arundel Medical Center
Annapolis, Maryland
- I'm interested
Kaiser Permanente - Largo Medical Center
Largo, Maryland
- Call 443-643-3010
UM Upper Chesapeake Medical Center
Bel Air, Maryland
This research site can be reached directly by phone. Call to ask about this study.
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- Call 443-777-7364
MedStar Franklin Square Medical Center/Weinberg Cancer Institute
Baltimore, Maryland
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- Call 240-964-1400
UPMC Western Maryland
Cumberland, Maryland
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- I'm interested
Lahey Clinic
Burlington, Massachusetts
- I'm interested
Lahey Clinic Peabody
Peabody, Massachusetts
- I'm interested
UMass Memorial Medical Center - University Campus
Worcester, Massachusetts
- Call 781-624-5000
Dana-Farber/Brigham and Women's Cancer Center at South Shore
South Weymouth, Massachusetts
This research site can be reached directly by phone. Call to ask about this study.
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- Call 877-338-7425
Dana Farber-Merrimack Valley
Methuen, Massachusetts
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- Call 617-789-2903
Dana-Farber Cancer Institute at Boston Medical Center - Brighton
Brighton, Massachusetts
This research site can be reached directly by phone. Call to ask about this study.
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- Call 978-283-4000
Addison Gilbert Hospital
Gloucester, Massachusetts
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- Call 978-922-3000
Beverly Hospital
Beverly, Massachusetts
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- Call 877-442-3324
Dana-Farber Cancer Institute
Boston, Massachusetts
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- Call 617-638-8265
Boston Medical Center
Boston, Massachusetts
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- I'm interested
Trinity Health Medical Center - Brighton
Brighton, Michigan
- I'm interested
Allegiance Health
Jackson, Michigan
- I'm interested
Bronson Battle Creek
Battle Creek, Michigan
- I'm interested
Bronson Methodist Hospital
Kalamazoo, Michigan
- I'm interested
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan
- I'm interested
Cancer Hematology Centers - Flint
Flint, Michigan
- I'm interested
Chelsea Hospital
Chelsea, Michigan
- Call 248-551-7695
Corewell Health Beaumont Troy Hospital
Troy, Michigan
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- Call 248-551-7695
Corewell Health Dearborn Hospital
Dearborn, Michigan
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- Call 248-551-7695
Corewell Health Farmington Hills Hospital
Farmington Hills, Michigan
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- I'm interested
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan
- I'm interested
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph, Michigan
- Call 616-391-1230
Corewell Health Lakeland Hospitals - Niles Hospital
Niles, Michigan
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Corewell Health Reed City Hospital
Reed City, Michigan
- Call 248-551-7695
Corewell Health William Beaumont University Hospital
Royal Oak, Michigan
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Genesys Hurley Cancer Institute
Flint, Michigan
- I'm interested
Hematology Oncology Consultants-Clarkston
Clarkston, Michigan
- I'm interested
Henry Ford Health Providence Novi Hospital
Novi, Michigan
- I'm interested
Henry Ford Health Providence Southfield Hospital
Southfield, Michigan
- I'm interested
Henry Ford Health Saint John Hospital
Detroit, Michigan
- I'm interested
Henry Ford Health Warren Hospital
Warren, Michigan
- I'm interested
Henry Ford Hospital
Detroit, Michigan
- I'm interested
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan
- I'm interested
Henry Ford Madison Heights Hospital - Breast
Warren, Michigan
- I'm interested
Henry Ford Medical Center-Columbus
Novi, Michigan
- I'm interested
Henry Ford River District Hospital
East China Township, Michigan
- I'm interested
Henry Ford Saint John Hospital - Academic
Grosse Pointe Woods, Michigan
- I'm interested
Henry Ford Saint John Hospital - Breast
Grosse Pointe Woods, Michigan
- I'm interested
Henry Ford Saint John Hospital - Macomb Medical
Macomb, Michigan
- I'm interested
Henry Ford Saint John Hospital - Van Elslander
Grosse Pointe Woods, Michigan
- I'm interested
Henry Ford Warren Hospital - Breast Macomb
Macomb, Michigan
- I'm interested
Henry Ford Warren Hospital - GLCMS
Warren, Michigan
- I'm interested
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan
- I'm interested
Hurley Medical Center
Flint, Michigan
- I'm interested
Huron Gastroenterology PC
Ypsilanti, Michigan
- I'm interested
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan
- I'm interested
Munson Medical Center
Traverse City, Michigan
- I'm interested
MyMichigan Medical Center Saginaw
Saginaw, Michigan
- I'm interested
MyMichigan Medical Center Tawas
Tawas City, Michigan
- I'm interested
Newland Medical Associates-Pontiac
Pontiac, Michigan
- I'm interested
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan
- I'm interested
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan
- I'm interested
Trinity Health Medical Center - Canton
Canton, Michigan
- I'm interested
Trinity Health Muskegon Hospital
Muskegon, Michigan
- I'm interested
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan
- I'm interested
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan
- I'm interested
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan
- I'm interested
University of Michigan Health - Sparrow Lansing
Lansing, Michigan
- I'm interested
University of Michigan Health - West
Wyoming, Michigan
- I'm interested
West Michigan Cancer Center
Kalamazoo, Michigan
- I'm interested
Mercy Hospital
Coon Rapids, Minnesota
- I'm interested
North Memorial Medical Health Center
Robbinsdale, Minnesota
- I'm interested
Hennepin County Medical Center
Minneapolis, Minnesota
- I'm interested
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota
- I'm interested
Essentia Health Sandstone
Sandstone, Minnesota
- I'm interested
Essentia Health Virginia Clinic
Virginia, Minnesota
- I'm interested
Abbott-Northwestern Hospital
Minneapolis, Minnesota
- I'm interested
Regions Hospital
Saint Paul, Minnesota
- I'm interested
Minnesota Oncology - Edina
Edina, Minnesota
- I'm interested
Saint Francis Regional Medical Center
Shakopee, Minnesota
- I'm interested
Minnesota Oncology - Burnsville
Burnsville, Minnesota
- Call 612-467-2800
Minneapolis VA Medical Center
Minneapolis, Minnesota
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
Ridgeview Medical Center
Waconia, Minnesota
- I'm interested
Fairview Southdale Hospital
Edina, Minnesota
- Call 218-786-3308
Essentia Health Hibbing Clinic
Hibbing, Minnesota
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Essentia Health - Deer River Clinic
Deer River, Minnesota
- I'm interested
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota
- I'm interested
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota
- I'm interested
Essentia Health Cancer Center
Duluth, Minnesota
- I'm interested
Baptist Memorial Hospital and Cancer Center-Oxford
Oxford, Mississippi
- I'm interested
Baptist Memorial Hospital and Cancer Center-Golden Triangle
Columbus, Mississippi
- Call 601-815-6700
University of Mississippi Medical Center
Jackson, Mississippi
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Baptist Memorial Hospital and Cancer Center-Union County
New Albany, Mississippi
- I'm interested
Baptist Memorial Hospital and Cancer Center-Desoto
Southhaven, Mississippi
- I'm interested
Baptist Cancer Center-Grenada
Grenada, Mississippi
- I'm interested
Washington University School of Medicine
St Louis, Missouri
- I'm interested
Freeman Health System
Joplin, Missouri
- I'm interested
Lake Regional Hospital
Osage Beach, Missouri
- Call 314-205-6936
Saint Luke's Hospital
Chesterfield, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 314-996-5569
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri
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Saint Francis Medical Center
Cape Girardeau, Missouri
- Call 314-251-7066
Mercy Hospital Saint Louis
St Louis, Missouri
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- I'm interested
Mercy Hospital South
St Louis, Missouri
- I'm interested
Heartland Regional Medical Center
Saint Joseph, Missouri
- Call 888-446-3729
Mercy Oncology and Hematology - Clayton-Clarkson
Ballwin, Missouri
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- I'm interested
Saint Luke's East - Lee's Summit
Lee's Summit, Missouri
- I'm interested
Siteman Cancer Center at Christian Hospital
St Louis, Missouri
- I'm interested
Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri
- Call 314-996-5569
Missouri Baptist Medical Center
St Louis, Missouri
This research site can be reached directly by phone. Call to ask about this study.
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- Call 314-996-5569
Missouri Baptist Sullivan Hospital
Sullivan, Missouri
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri
- Call 314-996-5569
Parkland Health Center - Farmington
Farmington, Missouri
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Siteman Cancer Center-South County
St Louis, Missouri
- Call 573-882-7440
MU Health - University Hospital/Ellis Fischel Cancer Center
Columbia, Missouri
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- I'm interested
Saint Luke's Hospital of Kansas City
Kansas City, Missouri
- I'm interested
Veteran's Affairs Medical Center - Saint Louis
St Louis, Missouri
- I'm interested
Bozeman Health Deaconess Hospital
Bozeman, Montana
- I'm interested
Billings Clinic Cancer Center
Billings, Montana
- I'm interested
Logan Health Medical Center
Kalispell, Montana
- I'm interested
Community Medical Center
Missoula, Montana
- I'm interested
Benefis Sletten Cancer Institute
Great Falls, Montana
- I'm interested
Community Hospital of Anaconda
Anaconda, Montana
- Call 402-334-4773
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha, Nebraska
This research site can be reached directly by phone. Call to ask about this study.
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- I'm interested
CHI Health Good Samaritan
Kearney, Nebraska
- Call 402-559-5600
Nebraska Medicine-Village Pointe
Omaha, Nebraska
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Cancer Partners of Nebraska
Lincoln, Nebraska
- I'm interested
Nebraska Medicine-Bellevue
Bellevue, Nebraska
- Call 402-354-5144
Nebraska Methodist Hospital
Omaha, Nebraska
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- I'm interested
University of Nebraska Medical Center
Omaha, Nebraska
- I'm interested
Fred and Pamela Buffett Cancer Center - Kearney
Kearney, Nebraska
- I'm interested
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada
- I'm interested
OptumCare Cancer Care at Charleston
Las Vegas, Nevada
- Call 603-224-2556
New Hampshire Oncology Hematology PA-Concord
Concord, New Hampshire
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- I'm interested
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire
- Call 800-339-6484
Solinsky Center for Cancer Care
Manchester, New Hampshire
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- I'm interested
The Valley Hospital - Luckow Pavilion
Paramus, New Jersey
- I'm interested
Valley Health System Ridgewood Campus
Ridgewood, New Jersey
- I'm interested
University of New Mexico Cancer Center
Albuquerque, New Mexico
- I'm interested
Presbyterian Rust Medical Center/Jorgensen Cancer Center
Rio Rancho, New Mexico
- Call 718-765-2500
Maimonides Medical Center
Brooklyn, New York
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- I'm interested
Upstate Cancer Center at Verona
Verona, New York
- I'm interested
Upstate Cancer Center at Oswego
Oswego, New York
- I'm interested
James J Peters VA Medical Center
The Bronx, New York
- Call 585-275-5830
University of Rochester
Rochester, New York
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- I'm interested
Montefiore Medical Center-Einstein Campus
The Bronx, New York
- I'm interested
Montefiore Medical Center - Moses Campus
The Bronx, New York
- Call 518-926-6700
Glens Falls Hospital
Glens Falls, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 516-326-7514
Good Samaritan University Hospital
West Islip, New York
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- I'm interested
Dickstein Cancer Treatment Center
White Plains, New York
- Call 914-366-1600
Phelps Memorial Hospital Center
Sleepy Hollow, New York
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Rochester General Hospital
Rochester, New York
- Call 315-472-7504
Hematology Oncology Associates of Central New York-East Syracuse
East Syracuse, New York
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- Call 315-472-7504
Hematology Oncology Associates of CNY at Camillus
Camillus, New York
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Roswell Park Cancer Institute
Buffalo, New York
- Call 516-734-8896
Northwell Health/Center for Advanced Medicine
Lake Success, New York
This research site can be reached directly by phone. Call to ask about this study.
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- Call 516-734-8896
Northwell Health Imbert Cancer Center
Bay Shore, New York
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- Call 315-464-5476
SUNY Upstate Medical Center-Community Campus
Syracuse, New York
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- Call 800-862-2215
Stony Brook University Medical Center
Stony Brook, New York
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- Call 315-464-5476
State University of New York Upstate Medical University
Syracuse, New York
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- I'm interested
The Cancer Institute at Saint Francis Hospital
East Hills, New York
- I'm interested
Cone Health Cancer Center
Greensboro, North Carolina
- Call 336-713-6771
Wake Forest University Health Sciences
Winston-Salem, North Carolina
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Cone Health Cancer Center at Alamance Regional
Burlington, North Carolina
- Call 704-872-3630
Wake Forest Baptist Health - Hematology Oncology - Statesville
Statesville, North Carolina
This research site can be reached directly by phone. Call to ask about this study.
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- Call 888-716-9259
Wake Forest University at Clemmons
Clemmons, North Carolina
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Cone Health Cancer Center at Drawbridge Parkway
Greensboro, North Carolina
- I'm interested
FirstHealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina
- I'm interested
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina
- I'm interested
CaroMont Regional Medical Center
Gastonia, North Carolina
- I'm interested
Cone Health MedCenter Asheboro
Asheboro, North Carolina
- I'm interested
Annie Penn Memorial Hospital
Reidsville, North Carolina
- Call 888-275-3853
Duke University Medical Center
Durham, North Carolina
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Sanford Broadway Medical Center
Fargo, North Dakota
- I'm interested
Sanford Roger Maris Cancer Center
Fargo, North Dakota
- I'm interested
Sanford Bismarck Medical Center
Bismarck, North Dakota
- I'm interested
Marietta Memorial Hospital
Marietta, Ohio
- I'm interested
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio
- I'm interested
Memorial Hospital
Marysville, Ohio
- I'm interested
Mercy Health - Perrysburg Hospital
Perrysburg, Ohio
- I'm interested
Mercy Health - Saint Anne Hospital
Toledo, Ohio
- I'm interested
Greater Dayton Cancer Center
Kettering, Ohio
- I'm interested
MetroHealth Medical Center
Cleveland, Ohio
- Call 937-569-7515
Miami Valley Cancer Care and Infusion
Greenville, Ohio
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- I'm interested
Miami Valley Hospital North
Dayton, Ohio
- I'm interested
Miami Valley Hospital South
Centerville, Ohio
- I'm interested
Miami Valley Hospital
Dayton, Ohio
- I'm interested
Mount Carmel East Hospital
Columbus, Ohio
- I'm interested
Mount Carmel Health Center West
Columbus, Ohio
- I'm interested
Genesis Healthcare System Cancer Care Center
Zanesville, Ohio
- I'm interested
North Coast Cancer Care
Sandusky, Ohio
- I'm interested
Fairfield Medical Center
Lancaster, Ohio
- I'm interested
ProMedica Flower Hospital
Sylvania, Ohio
- I'm interested
Dayton Physician LLC - Englewood
Dayton, Ohio
- I'm interested
Saint Ann's Hospital
Westerville, Ohio
- I'm interested
Cleveland Clinic Wooster Family Health and Surgery Center
Wooster, Ohio
- I'm interested
Cleveland Clinic Foundation
Cleveland, Ohio
- I'm interested
Cleveland Clinic Cancer Center/Fairview Hospital
Cleveland, Ohio
- I'm interested
Cleveland Clinic Cancer Center Mansfield
Mansfield, Ohio
- I'm interested
Cleveland Clinic Cancer Center Independence
Independence, Ohio
- I'm interested
Cleveland Clinic Akron General
Akron, Ohio
- I'm interested
South Pointe Hospital
Warrensville Heights, Ohio
- I'm interested
Southern Ohio Medical Center
Portsmouth, Ohio
- I'm interested
Springfield Regional Cancer Center
Springfield, Ohio
- I'm interested
Strecker Cancer Center-Belpre
Belpre, Ohio
- I'm interested
The Mark H Zangmeister Center
Columbus, Ohio
- Call 888-874-7000
Trinity's Tony Teramana Cancer Center
Steubenville, Ohio
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Aultman Health Foundation
Canton, Ohio
- I'm interested
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio
- I'm interested
Adena Regional Medical Center
Chillicothe, Ohio
- I'm interested
Licking Memorial Hospital
Newark, Ohio
- I'm interested
Knox Community Hospital
Mount Vernon, Ohio
- I'm interested
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma
- Call 877-231-4440
Cancer Centers of Southwest Oklahoma Research
Lawton, Oklahoma
This research site can be reached directly by phone. Call to ask about this study.
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- Call 405-752-3402
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma
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- Call 405-773-6613
Integris Cancer Institute of Oklahoma
Oklahoma City, Oklahoma
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Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon
- I'm interested
Good Samaritan Hospital
Corvallis, Oregon
- I'm interested
Providence Portland Medical Center
Portland, Oregon
- Call 541-472-7000
Three Rivers Community Hospital
Grants Pass, Oregon
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- I'm interested
Kaiser Permanente Northwest
Portland, Oregon
- I'm interested
Asante Rogue Regional Medical Center
Medford, Oregon
- I'm interested
Providence Saint Vincent Medical Center
Portland, Oregon
- I'm interested
Riddle Memorial Hospital
Media, Pennsylvania
- Call 717-217-6020
WellSpan Medical Oncology and Hematology
Chambersburg, Pennsylvania
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Pocono Medical Center
East Stroudsburg, Pennsylvania
- I'm interested
Divine Providence Hospital
Williamsport, Pennsylvania
- Call 412-784-4900
UPMC-Saint Margaret
Pittsburgh, Pennsylvania
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Sechler Family Cancer Center
Lebanon, Pennsylvania
- I'm interested
Carlisle Regional Cancer Center
Carlisle, Pennsylvania
- Call 412-502-3920
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania
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- Call 412-367-6454
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania
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- Call 800-533-8762
UPMC-Mercy Hospital
Pittsburgh, Pennsylvania
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Paoli Memorial Hospital
Paoli, Pennsylvania
- Call 814-534-4724
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania
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UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania
- Call 412-653-8100
UPMC West Mifflin-Cancer Center Jefferson
West Mifflin, Pennsylvania
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- Call 800-598-4282
UPMC Susquehanna
Williamsport, Pennsylvania
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UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania
- Call 717-721-4840
Ephrata Cancer Center
Ephrata, Pennsylvania
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- I'm interested
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania
- Call 717-724-6760
UPMC Memorial
York, Pennsylvania
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- Call 412-647-8073
UPMC Hillman Cancer Center
Pittsburgh, Pennsylvania
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- I'm interested
UPMC Hillman Cancer Center - Part of Frick Hospital
Mount Pleasant, Pennsylvania
- I'm interested
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania
- I'm interested
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania
- I'm interested
IRMC Cancer Center
Indiana, Pennsylvania
- Call 877-441-7957
WellSpan Health-York Hospital
York, Pennsylvania
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- I'm interested
UPMC Hillman Cancer Center in Coraopolis
Moon Township, Pennsylvania
- I'm interested
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania
- Call 800-836-0388
Guthrie Medical Group PC-Robert Packer Hospital
Sayre, Pennsylvania
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- I'm interested
Lankenau Medical Center
Wynnewood, Pennsylvania
- I'm interested
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania
- I'm interested
Geisinger Cancer Services-Pottsville
Pottsville, Pennsylvania
- I'm interested
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania
- I'm interested
Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania
- I'm interested
Geisinger Medical Center
Danville, Pennsylvania
- I'm interested
Geisinger Medical Center-Cancer Center Hazleton
Hazleton, Pennsylvania
- I'm interested
Temple University Hospital
Philadelphia, Pennsylvania
- I'm interested
Community Medical Center
Scranton, Pennsylvania
- I'm interested
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania
- Call 717-632-1559
WellSpan Medical Oncology and Hematology
Hanover, Pennsylvania
This research site can be reached directly by phone. Call to ask about this study.
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- Call 877-441-7957
Adams Cancer Center
Gettysburg, Pennsylvania
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- Call 610-988-9323
Reading Hospital
West Reading, Pennsylvania
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- I'm interested
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon, Pennsylvania
- I'm interested
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania
- I'm interested
Fox Chase Cancer Center - East Norriton Hospital Outpatient Center
East Norriton, Pennsylvania
- I'm interested
Fox Chase Cancer Center
Philadelphia, Pennsylvania
- I'm interested
Geisinger Cancer Center Dickson City
Dickson City, Pennsylvania
- I'm interested
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania
- I'm interested
UPMC Cancer Center-Washington
Washington, Pennsylvania
- I'm interested
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania
- Call 724-838-1900
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania
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- Call 724-230-3030
UPMC Cancer Center-Natrona Heights
Natrona Heights, Pennsylvania
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- Call 814-676-7900
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania
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- Call 412-647-8073
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania
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- Call 877-441-7957
WellSpan Health-York Cancer Center
York, Pennsylvania
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- I'm interested
UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania
- I'm interested
UPMC Altoona
Altoona, Pennsylvania
- I'm interested
Roger Williams Medical Center
Providence, Rhode Island
- Call 401-444-1488
Rhode Island Hospital
Providence, Rhode Island
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- I'm interested
Bon Secours Saint Francis Hospital
Charleston, South Carolina
- I'm interested
Saint Joseph's/Candler - Bluffton Campus
Bluffton, South Carolina
- I'm interested
Lexington Health
West Columbia, South Carolina
- I'm interested
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina
- I'm interested
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina
- I'm interested
Prisma Health Cancer Institute - Greer
Greer, South Carolina
- I'm interested
Prisma Health Cancer Institute - Faris
Greenville, South Carolina
- I'm interested
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina
- I'm interested
Prisma Health Cancer Institute - Easley
Easley, South Carolina
- I'm interested
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina
- I'm interested
SMC Center for Hematology Oncology Union
Union, South Carolina
- I'm interested
South Carolina Cancer Specialists PC
Hilton Head Island, South Carolina
- I'm interested
Spartanburg Medical Center
Spartanburg, South Carolina
- I'm interested
Gibbs Cancer Center-Gaffney
Gaffney, South Carolina
- I'm interested
Gibbs Cancer Center-Pelham
Greer, South Carolina
- I'm interested
Medical University of South Carolina
Charleston, South Carolina
- I'm interested
Saint Francis Cancer Center
Greenville, South Carolina
- I'm interested
Saint Francis Hospital
Greenville, South Carolina
- I'm interested
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota
- I'm interested
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota
- I'm interested
Baptist Memorial Hospital and Cancer Center-Collierville
Collierville, Tennessee
- I'm interested
Baptist Memorial Hospital and Cancer Center-Memphis
Memphis, Tennessee
- I'm interested
Ballad Health Cancer Care - Kingsport
Kingsport, Tennessee
- I'm interested
Regional Cancer Center at Johnson City Medical Center
Johnson City, Tennessee
- I'm interested
Houston Methodist The Woodlands Hospital
The Woodlands, Texas
- Call 832.522.6070
Houston Methodist West Hospital
Houston, Texas
This research site can be reached directly by phone. Call to ask about this study.
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- Call 713.790.3311
Houston Methodist Hospital
Houston, Texas
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- Call 325-670-6340
Hendrick Medical Center
Abilene, Texas
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- I'm interested
Parkland Memorial Hospital
Dallas, Texas
- I'm interested
Houston Methodist San Jacinto Hospital
Baytown, Texas
- Call 281.274.7000
Houston Methodist Sugar Land Hospital
Sugar Land, Texas
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- I'm interested
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas
- I'm interested
UT Southwestern Simmons Cancer Center - RedBird
Dallas, Texas
- I'm interested
Dartmouth Cancer Center - North
Saint Johnsbury, Vermont
- I'm interested
Ballad Health Cancer Care - Norton
Norton, Virginia
- I'm interested
Kaiser Permanente Tysons Corner Medical Center
McLean, Virginia
- I'm interested
Ballad Health Cancer Care - Bristol
Bristol, Virginia
- I'm interested
Centra Alan B Pearson Regional Cancer Center
Lynchburg, Virginia
- Call 540-332-5960
Augusta Health Center for Cancer and Blood Disorders
Fishersville, Virginia
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- I'm interested
Kaiser Permanente-Caton Hill Medical Center
Woodbridge, Virginia
- I'm interested
Valley Medical Center
Renton, Washington
- I'm interested
Kadlec Clinic Hematology and Oncology
Kennewick, Washington
- I'm interested
West Virginia University Healthcare
Morgantown, West Virginia
- Call 304-243-6442
Wheeling Hospital/Schiffler Cancer Center
Wheeling, West Virginia
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- I'm interested
United Hospital Center
Bridgeport, West Virginia
- I'm interested
Camden Clark Medical Center
Parkersburg, West Virginia
- I'm interested
Edwards Comprehensive Cancer Center
Huntington, West Virginia
- I'm interested
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin
- I'm interested
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin
- I'm interested
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - Johnson Creek
Johnson Creek, Wisconsin
- I'm interested
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin
- I'm interested
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin
- I'm interested
Aurora Sinai Medical Center
Milwaukee, Wisconsin
- I'm interested
Aurora West Allis Medical Center
West Allis, Wisconsin
- I'm interested
Ascension Calumet Hospital-Chilton
Chilton, Wisconsin
- I'm interested
Duluth Clinic Ashland
Ashland, Wisconsin
- I'm interested
Cancer Center of Western Wisconsin
New Richmond, Wisconsin
- I'm interested
Ascension Columbia Saint Mary's Hospital-Milwaukee Campus
Milwaukee, Wisconsin
- I'm interested
Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon
Mequon, Wisconsin
- I'm interested
Marshfield Medical Center - Weston
Weston, Wisconsin
- I'm interested
Gundersen Lutheran Medical Center
La Crosse, Wisconsin
- I'm interested
Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh
Oshkosh, Wisconsin
- I'm interested
Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton
Appleton, Wisconsin
- I'm interested
Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield
Brookfield, Wisconsin
- I'm interested
Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa
Wauwatosa, Wisconsin
- Call 715-422-7718
Aspirus Cancer Care - Wisconsin Rapids
Wisconsin Rapids, Wisconsin
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- I'm interested
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin
- Call 414-805-3666
Medical College of Wisconsin
Milwaukee, Wisconsin
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- I'm interested
Aspirus Cancer Care-Antigo-Volm Cancer Center
Antigo, Wisconsin
- I'm interested
Ascension All Saints Hospital-Spring Street-Racine
Racine, Wisconsin
- I'm interested
Aspirus Cancer Care-Rhinelander-James Beck Cancer Center
Rhinelander, Wisconsin
- Call 877-405-6866
Aspirus Cancer Care-Wausau
Wausau, Wisconsin
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- I'm interested
Aspirus Medford Hospital
Medford, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Sturgeon Bay
Sturgeon Bay, Wisconsin
- I'm interested
Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson
Franklin, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Saint Mary's
Green Bay, Wisconsin
- I'm interested
Saint Vincent Hospital Cancer Center at Oconto Falls
Oconto Falls, Wisconsin
- I'm interested
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin
- I'm interested
Aurora BayCare Medical Center
Green Bay, Wisconsin
- I'm interested
Aurora Cancer Care-Grafton
Grafton, Wisconsin
- I'm interested
ProHealth D N Greenwald Center
Mukwonago, Wisconsin
- Call 262-928-7878
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin
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- Call 262-928-7632
ProHealth Waukesha Memorial Hospital
Waukesha, Wisconsin
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- I'm interested
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin
- Call 920-435-8326
Bellin Memorial Hospital
Green Bay, Wisconsin
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- Call 608-256-1901
William S Middleton VA Medical Center
Madison, Wisconsin
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Marshfield Medical Center - Minocqua
Minocqua, Wisconsin
- I'm interested
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin
- I'm interested
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin
- I'm interested
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin
- I'm interested
Aurora Cancer Care-Racine
Racine, Wisconsin
- I'm interested
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin
- I'm interested
Aurora Health Care Germantown Health Center
Germantown, Wisconsin
- I'm interested
ThedaCare Regional Medical Center - Neenah
Neenah, Wisconsin
- I'm interested
ThedaCare Regional Cancer Center
Appleton, Wisconsin
- I'm interested
Aurora Medical Center in Summit
Summit, Wisconsin
- I'm interested
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin
Who can participate
Inclusion criteria
- ✓A female of childbearing potential is a sexually mature female who:
- ✓Has not undergone a hysterectomy or bilateral oophorectomy; or
- ✓Has not been naturally postmenopausal for at least 12 consecutive months (i.e., has had menses at any time in the preceding 12 consecutive months)
- ✓Local testing of EGFR with no EGFR exon 19 deletion or EGFR L858 R mutation (applicable to non-squamous patients only)
- ✓Local testing of ALK with no ALK rearrangement (failed testing is considered negative) (applicable to non-squamous patients only)
- ✓Local testing of PD-L1 immunohistochemistry (IHC) using one of the following assays: DAKO 22C3, DAKO 28-8, EIL3N or SP263
- ✓Completely resected stage IIA, IIB IIIA or IIIB (T3-4N2) non-small cell lung cancer (NSCLC) (squamous or non-squamous) with negative margins (complete R0 resection). Patients will be staged according to the 8th edition of the American Joint Committee on Cancer (AJCC) Staging Manual, 2017
- ✓Note: Patients with pathologic N2 disease, completely resected, are eligible. However, patients known to have N2 disease prior to surgery are not eligible; guidelines do not recommend up-front surgery for this population
- ✓Complete recovery from surgery. Registration to A081801 must be 30-77 days following surgery
- ✓No prior neoadjuvant or adjuvant therapy for current lung cancer diagnosis
- ✓No prior allogeneic tissue/solid organ transplant
- ✓Patients must NOT have uncontrolled intercurrent illness including, but not limited to, serious ongoing or active infection, symptomatic congestive heart failure, uncontrolled cardiac arrhythmia, unstable angina pectoris, that would limit compliance with study requirements
- ✓No current pneumonitis or history of (non-infectious) pneumonitis that required steroids
- ✓Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial
- ✓Age \>= 18 years
- ✓Eastern Cooperative Oncology Group (ECOG) performance status (PS): 0-1
- ✓No active auto-immune disease that has required systemic treatment within the last 2 years (e.g., disease-modifying agents, corticosteroids, or immunosuppressive drugs). Replacement therapy (e.g., thyroxine, insulin, or physiologic corticosteroid release therapy for adrenal or pituitary insufficiency) is not considered a form of systemic treatment
- ✓Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects
- ✓Therefore, for women of childbearing potential only, a negative pregnancy test done =\< 7 days prior to registration is required
- ✓No patients with a "currently active" second malignancy that is progressing or has required active treatment within the last 3 years. Participants with non-melanoma skin cancers, low grade or low-risk cancers, or stage I malignancies not requiring systemic therapy (e.g., prostate cancer requiring only observation or superficial bladder cancer), or carcinoma in situ (e.g., breast carcinoma or cervical cancer in situ) that have undergone potentially curative therapy are eligible
- ✓No hypersensitivity (\>= grade 3) to pembrolizumab and/or any of its excipients
- ✓No live vaccine within 30 days prior to registration. Examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, varicella/zoster (chicken pox), yellow fever, rabies, Bacillus Calmette-Guerin (BCG), and typhoid vaccine. Seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., FluMist) are live attenuated vaccines and are not allowed
- ✓No known hepatitis C virus (defined as HCV ribonucleic acid \[RNA\] \[qualitative\] is detected) infection or known history of hepatitis B (defined as hepatitis B surface antigen \[HBsAg\] reactive)
- ✓Absolute neutrophil count (ANC) \>= 1,500/mm\^3
- ✓Platelet count \>= 100,000/mm\^3
- ✓Hemoglobin \>= 8 gm/dl
- ✓Calculated (Calc.) creatinine clearance \>= 45 mL/min
- ✓Total bilirubin =\< 1.5 x upper limit of normal (ULN)
- ✓Aspartate aminotransferase (AST) / alanine aminotransferase (ALT) =\< 2.5 x upper limit of normal (ULN)
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.