The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors
Sponsored by Arizona State University
About this study
The investigators are interested in finding out how Prolonged Nightly Fasting (PNF) and/or health education may impact health and cancer recovery for breast cancer patients and survivors.
The purpose of this innovative, remotely-delivered pilot randomized controlled trial (RCT) is to explore the use of an 8-week prolonged nightly fasting (PNF) intervention, as compared to a Health Education-Only (HED-Only) control condition, among ethnically and racially diverse (≥50% Black, Hispanic, and/or Native American) breast cancer survivors (BCSs) with cancer-related cognitive impairment (CRCI) to examine changes in cognitive function, sleep, insomnia and health-related quality of life (i.e., mental and physical). Additionally, intervention feasibility will be assessed among the PNF participants. All participants will receive health education (HED) throughout. BCSs living with CRCI (N=60) will be recruited nationwide and randomized 1:1 into the PNF or HED-Only groups. Linear mixed m…
Where this study is enrolling
- I'm interested
Arizona State University
Phoenix, Arizona
Who can participate
Inclusion criteria
- ✓1. ≥18 years old
- ✓2. diagnosed with breast cancer (all stages included)
- ✓3. ≥3 months post neoadjuvant or adjuvant chemotherapy (maintenance or palliative systemic therapy is included)
- ✓4. score ≤30 or lower on the Patient Reported Outcome Measurement Information System Cognitive Function Short Form 8a (sr-CRCI)
- ✓5. able to speak/understand English
- ✓6. have access to a computer and Wi-Fi
- ✓7. live within the United States
- ✓8. Identifies as female
- ✓9. willing and able to fully participate in the study
Exclusion criteria
- ✕1. type 1 diabetes
- ✕2. actively enrolled in formal diet/weight loss program
- ✕3. previous bariatric surgery
- ✕4. eating disorder history
- ✕5. night shift work
- ✕6. pregnant, breast feeding, or trying to get pregnant
- ✕7. dementia, psychological, psychiatric, or neurological diagnoses
- ✕8. active brain or central nervous system disease
- ✕9. prior or current use of memory enhancing medications
- ✕10. history or current brain radiation
- ✕11. frequently fasting for 12+ hours every night
- ✕13\) history of hypoglycemia 14) depression screening on PHQ9 with a score of 20 or greater across all 9 questions OR anything other than 0 on question 9
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.