Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
Sponsored by Georgia State University
About this study
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
In the U.S., 35.3 million adults have type 2 diabetes mellitus (T2DM) and 96 million have prediabetes. Eight out of 10 people with T2DM die from cardiovascular disease. People with T2DM also have a 50% higher risk of developing dementia compared to healthy counterparts. Further, studies show that gut microbes play a major role in the development of T2DM. Prevention and treatment of T2DM focus on lifestyle changes including dietary modifications such as increased consumption of deep-colored fruits like berries. Blueberries are rich in fiber and phytochemicals and have several health benefits. We and others have shown that blueberry intake improves heart health in healthy men, hypertensive postmenopausal women, and men and women with metabolic syndrome. Yet, a comprehensive study in women wi…
Where this study is enrolling
- I'm interested
Georgia State University
Atlanta, Georgia
Who can participate
Inclusion criteria
- ✓Women aged 20-65 years old
- ✓Prediabetes (fasting blood glucose 100-125 mg/dL and/or HbA1c percentage between 5.7-6.4)
- ✓Body Mass Index between 25-30 kg/m\^2
Exclusion criteria
- ✕Allergies to berries
- ✕Use of insulin, antidiabetic, antibiotics, and anti-inflammatory drugs
- ✕Active cancer, gastrointestinal, renal, thyroid, stage 1 \& 2 hypertension and other cardiovascular diseases, neurological diseases, or severe head injury
- ✕Smoking
- ✕Consumes greater than 2 alcoholic beverages per day
- ✕Consumes antioxidant, probiotic, and prebiotic supplements
- ✕Pregnant or Lactating
- ✕Actively participating in a weight loss program
- ✕Currently taking berry supplements or recently participated in another study taking berry supplements
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.