Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
Sponsored by Georgia State University
About this study
The purpose of the study is to determine the effectiveness of wild blueberries on cardiovascular health, cognitive function, and gut microbiota composition in non-Hispanic Black and White adults with elevated blood pressure.
Hypertension (HTN), or high blood pressure (BP) is a major modifiable risk factor for heart disease, the leading cause of death worldwide. In the U.S., 121.5 million adults have high BP and only 25% have their BP under control. The 2022 Heart Disease and Stroke Statistics indicated that the incidence of high BP was higher among non-Hispanic Black (NHB) compared to non-Hispanic White (NHW) adults. Berries are rich in fiber and phytochemicals and have several health benefits. A 14-year follow-up of the Nurses' Health Study I and II and the Health Professional Follow-Up Study revealed a significant reduction in the risk of HTN (8%) among individuals in the highest quintile of anthocyanin intake compared to the lowest quintile. Blueberries are rich in fiber and phytochemicals that may be respo…
Where this study is enrolling
- I'm interested
Georgia State University
Atlanta, Georgia
Who can participate
Inclusion criteria
- ✓Individuals 45-65 years of age
- ✓Diagnosis of elevated blood pressure or stage 1 hypertension (systolic blood pressure = 120-139 mmHg and/or diastolic blood pressure = 80-89 mmHg) for at least 6 months
- ✓BMI 25-35 kg/m2 via anthropometric measurements.
- ✓Ability to give consent
Exclusion criteria
- ✕Allergies to berries
- ✕Use of one hypertensive drug for less than three months
- ✕Use of more than one anti-hypertensive or statin drug, insulin, antibiotics, and anti-inflammatory drugs, active cancer, gastrointestinal, renal, cardiovascular, thyroid, and neurological disorders or severe head injury
- ✕Smoking
- ✕Alcohol consumption (\>2 drinks/day)
- ✕Consuming antioxidant, probiotic, and prebiotic supplements
- ✕Pregnant or lactating
- ✕Participating in a weight loss program
Only the research team can confirm whether you qualify. The intake questionnaire is the best way to find out.
Completing a questionnaire on Clinably does not enroll you in a clinical trial or confirm your eligibility. Only the research team can determine whether you qualify to participate. These results are based on the information you provide and are intended to help you start a conversation with the research team.
Trial data sourced from ClinicalTrials.gov.